Results 81 to 90 of about 1,573,473 (242)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

(Table 4) Physical properties of sediment at DSDP Hole 93-604 [PDF]

, 1987
(Table 4) Physical properties of sediment at DSDP Hole 93 ...
Mark W Johns (7982591), Biart, Brian N M, Dean A Dunn (7982411), Johns, Mark W, Dunn, Dean A, Brian N M Biart (7982588)   +5 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Investment and Saving Opportunities for Different Socio-Economic Groups in Medieval and Early Modern Europe

Jahrbuch für Wirtschaftsgeschichte
This special issue focuses on the financial behaviour of different participants in European medieval and early modern financial markets. It extends our knowledge of the financial strategies employed by households, merchants, charities, city governments ...
Nicolussi-Köhler Stephan, Conti Marco, Wandschneider Kirsten   +2 more
doaj   +1 more source

New Instrument for Oral Hygiene of Children with Cleft Lip and Palate

Applied Sciences, 2018
Patients with cleft lip and palate (CLP) have several oral alterations that make the removal of bacterial plaque in the cleft area difficult, which is the main cause of the high incidence of oral health problems.
Rita Rodrigues, Maria Helena Fernandes, António Bessa Monteiro, Rowney Furfuro, Cátia Carvalho Silva, César Soares, Ricardo Vardasca, Joaquim Mendes, Maria Conceição Manso   +8 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Politics, Investments and Public Spending in Bologna (End of 13th – First Half of 14th Century)

Jahrbuch für Wirtschaftsgeschichte
Not all major Italian cities of the late Middle Ages could rely on an established and organised system of public debt like Florence, Venice, Genoa, and others.
Conti Marco
doaj   +1 more source

(Table 2) Physical properties of sediment at DSDP Hole 93-603B [PDF]

, 1987
(Table 2) Physical properties of sediment at DSDP Hole 93 ...
Mark W Johns (7982591), Biart, Brian N M, Dean A Dunn (7982411), Johns, Mark W, Dunn, Dean A, Brian N M Biart (7982588)   +5 more
core   +1 more source

Reflexiones a la Ley n.° 294/93, Evaluación de impacto ambiental

Revista Jurídica, 2017
El objetivo tradicional de las normas ambientales ha sido la prevención de consecuencias graves para la salud y en especial de accidentes desastrosos, en ese sentido, la evaluación de impacto ambiental consiste como ya lo dijimos anteriormente, en un ...
Miguel Oscar Bajac
doaj   +4 more sources