Results 31 to 40 of about 1,671,368 (287)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Using a Non-Contact Sensor to Delineate Management Zones in Vineyards and Validation with the Rasch Model

Sensors, 2023
The production of high-quality wines is one of the primary goals of modern oenology. In this regard, it is known that the potential quality of a wine begins to be determined in the vineyard, where the quality of the grape, initially, and later that of ...
Francisco J. Moral, Francisco J. Rebollo, João Serrano   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Characteristics of veterinary practitioners (n = 94).

, 2013
Characteristics of veterinary practitioners (n = 94).
Robert F. Smith (357365), Martin J. Green (407496), Helen M. Higgins (407494), Eamonn Ferguson (407495)   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Characteristics of the patients (n = 94).

, 2015
Characteristics of the patients (n = 94).
Ken-ichirou Morishige (689896), Hiroshi Makino (484869), Aska Toda (689892), Chifumi Ohyagi-Hara (689887), Seiji Mabuchi (689894), Noriko Suzuki (315835), Koji Nakamura (689890), Eiichi Morii (162029), Ikuko Sawada (689891), Kae Hashimoto (689893), Erika Nakatsuka (689888), Tsuyoshi Ohta (689895), Aki Isobe (689884), Tadashi Kimura (392934), Yasuto Kinose (689886), Tomoko Mizuno (308626), Hirohisa Kurachi (689897), Kenjiro Sawada (689885), Tomonori Ogura (689889)   +18 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Interactive effects of elevated atmospheric CO2 and UV-B radiation: A multi-level study on marine diatom Skeletonema pseudocostatum

Ecotoxicology and Environmental Safety
Climate change as a result of increases in greenhouse gas emissions, such as CO2, is causing significant alteration in global environmental conditions, including ocean acidification (OA).
Li Xie, Ailbhe Macken, Knut Erik Tollefsen   +2 more
doaj   +1 more source