Results 51 to 60 of about 15,580,988 (193)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Ato n. 119/CSJT.GP.SE, de 29 de abril de 2013

open access: yes, 2013
Define os membros do Comitê Gestor Nacional do Sistema Processo Judicial Eletrônico da Justiça do Trabalho (PJe-JT) de que trata o art. 34 da Resolução n. 94/CSJT, de 23 de março de 2012.AlteradoAlterado pelo Ato n.
Conselho Superior da Justiça do Trabalho (Brasil) (CSJT)
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

GSI-contributions to HCI-94

open access: yes, 1994
SIGLEAvailable from TIB Hannover: RO 801(94-80) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Mokler, P.H. (ed.)   +1 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Figs. 94‐99. Egg micrographs. 94‐96. N. hamata. 94. Egg, 95. Collar, 96. Lid. 97‐99. N. hubleyi. 97. Egg, 98. Collar, 99 in New Species And Records Of Neoperla (Plecoptera: Perlidae) From Vietnam

open access: yes, 2008
Figs. 94‐99. Egg micrographs. 94‐96. N. hamata. 94. Egg, 95. Collar, 96. Lid. 97‐99. N. hubleyi. 97. Egg, 98. Collar, 99. Lid.Published as part of Stark, Bill P.
Sivec, Ignac, Stark, Bill P.
core   +1 more source

Resolução Administrativa n. 2882, de 9 de março de 2026

open access: yes
Referenda o Ato n. 94/TST.GP, de 18 de fevereiro de 2026, que atribui ao Espaço do Servidor do Tribunal Superior do Trabalho o nome do Exmo. Sr.
Brasil. Tribunal Superior do Trabalho (TST)
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

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