Results 41 to 50 of about 1,671,368 (287)

Reasons for refusal TST among HCWs (N = 94).

, 2014
Reasons for refusal TST among HCWs (N = 94).
Ying Deng (86469), Jianmin Liu (285775), Junguo Chen (621704), Yibin Hao (621702), Lei Gao (6566), Xianli Zhao (621703), Xiangwei Li (218626), Yu Yang (83671), Li Zhang (8200), Jie Lu (139953), Feng Zhou (76988)   +10 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Geographical Aspects of Diphtheria in England and Wales: Immunisation and the Spatial Sequence of Retreat to Effective Elimination, 1921 to 1964

Jahrbuch für Wirtschaftsgeschichte
On the eve of the Second World War, an average of 5,000 hospital beds in England and Wales were occupied at any one time by diphtheria patients, and the annual costs of their treatment was £1 million.
Smallman-Raynor Matthew, Jewitt Sarah, Cliff Andrew D.   +2 more
doaj   +1 more source

Tension gastrothorax in late diagnosis of congenital diaphragmatic hernia

Radiology Case Reports
Tension gastrothorax is a rare but potentially fatal complication of congenital diaphragmatic hernia, frequently mistaken for tension pneumothorax. Early recognition is essential to avoid delays in definitive management.
Yasmine Houas, MD, Hela Oueslati, MD, Nada Sghairoun, MD, Asma Guitouni, MD, Riadh Jouini, MD   +4 more
doaj   +1 more source

Identification of the N-terminal Peptide Binding Site of Glucose-regulated Protein 94 [PDF]

Journal of Biological Chemistry, 2004
Because the stress protein GRP94 can augment presentation of peptides to T cells, it is important to define how it, as well as all other HSP90 family members, binds peptides. Having previously shown that the N-terminal half of GRP94 can account for the peptide binding activity of the full-length protein, we now locate this binding site by testing ...
Gidalevitz, T., Biswas, C., Ding, H., Schneidman-Duhovny, D., Wolfson, H.J., Stevens, F., Radford, S.E., Argon, Y.   +7 more
openaire   +4 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Investment and Saving Opportunities for Different Socio-Economic Groups in Medieval and Early Modern Europe

Jahrbuch für Wirtschaftsgeschichte
This special issue focuses on the financial behaviour of different participants in European medieval and early modern financial markets. It extends our knowledge of the financial strategies employed by households, merchants, charities, city governments ...
Nicolussi-Köhler Stephan, Conti Marco, Wandschneider Kirsten   +2 more
doaj   +1 more source

A multi-tiered workflow for constructing a quantitative adverse outcome pathway network for gamma radiation-induced reproductive inhibition in Lemna minor

Ecotoxicology and Environmental Safety
While numerous qualitative adverse outcome pathways (AOPs) have been developed to describe the progressive toxicity of ionizing radiation, quantitative AOPs (qAOPs) to detail how effects quantitatively propagate from the initial molecular interaction to ...
Li Xie, Knut Erik Tollefsen
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Wood-based Businesses and the Economic Development of Europe in the Nineteenth and Twentieth Centuries – An Introduction

Jahrbuch für Wirtschaftsgeschichte
This introduction sketches out what relevance wood and wood products have had in Europe’s industrial societies. It also summarizes some peculiarities of the wood-based businesses caused by both the materiality of wood and the ecologies of forests.
Bemmann Martin
doaj   +1 more source