Results 41 to 50 of about 3,450 (152)
ABSTRACT The missense SNP NC_000004.12:g.102267552C>T (also known as SLC39A8.p.(Ala391Thr), rs13107325) in SLC39A8 encodes a zinc transporter. This SNP has been linked to schizophrenia and is the likely causal variant for one of the genome‐wide association loci associated with the disorder. Using regression analyses, we tested whether the schizophrenia‐
Sophie E. Smart +12 more
wiley +1 more source
The 'Foce' monumental cemetery in Sanremo: mirror of the city as outstanding tourist destination during the Belle Epoque (1880-1915) [PDF]
The monumental cemetery of Sanremo, was founded in 1838 and now counts about 2000 graves, one third of which belongs to foreigners, evidences of the city as outstanding tourist destination.
Salvini, Silvia
core +3 more sources
DNA-condensation, redissolution and mesocrystals induced by tetravalent counterions
The distance-resolved effective interaction potential between two parallel DNA molecules is calculated by computer simulations with explicit tetravalent counterions and monovalent salt.
+12 more
core +1 more source
Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease [PDF]
Oxidative stress is proposed as an important factor in osteoarthritis (OA). To investigate the expression of the three superoxide dismutase (SOD) antioxidant enzymes in OA.
Boot-Handford, Raymond P. +9 more
core +1 more source
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada +2 more
wiley +1 more source
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey +6 more
wiley +1 more source
Palamas and Florensky: The Metaphysics of the Heart in Patristic and Russian Philosophical Tradition [PDF]
Тhis paper focuses on the philosophical issue known as the metaphysics of the heart within Orthodox Christianity – both Russian and Byzantie versions. Russian religious thought is based on patristic tradition.
Kroczak, Justyna
core +1 more source
ABSTRACT Inflation in genome‐wide association studies (GWAS) summary statistics represents a major challenge, for which correction methods have been developed. These include the genomic control (GC) method, which uses the λ‐value to correct summary statistics, and the linkage disequilibrium score regression (LDSR) method, which uses the LDSR intercept.
Archit Singh +11 more
wiley +1 more source
ABSTRACT A large proportion of patients undergoing cognitive behavior therapy (CBT) for obsessive‐compulsive disorder (OCD) do not respond sufficiently to treatment. Identifying predictors for change in symptom severity after treatment could inform clinical decision‐making, allow for better‐tailored interventions, and avoid treatment failure.
Julia Bäckman +39 more
wiley +1 more source
Cross‐Sectional Brain Age Assessments Are Limited in Predicting Future Brain Change
Multimodal imaging data of 39,325 UK Biobank participants with 2,520 follow‐ups provide insufficient evidence to conclude that brain age reflects the rate of anatomical brain aging. However, modality‐specific differences in brain ages reflect the cross‐sectional state of the brain, highlighting diffusion and multimodal MRI brain age as potentially ...
Max Korbmacher +9 more
wiley +1 more source

