Results 111 to 120 of about 326,728 (258)

The clinical implication of CD45RA+ naïve T cells and CD45RO+ memory T cells in advanced pancreatic cancer: a proxy for tumor biology and outcome prediction

open access: yesCancer Medicine, 2019
Naïve and memory T cells play a pivotal role in solid tumor pathogenesis but their role in pancreatic cancer progression remains elusive. Thus, we aimed to investigate their clinical potential in advanced pancreatic cancer (APC).
Junjie Hang   +9 more
doaj   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang   +5 more
wiley   +1 more source

Divergent populations of HIV-infected naive and memory CD4+ T cell clones in children on antiretroviral therapy

open access: yesThe Journal of Clinical Investigation
BACKGROUND Naive cells comprise 90% of the CD4+ T cell population in neonates and exhibit distinct age-specific capacities for proliferation and activation.
Mary Grace Katusiime   +12 more
doaj   +1 more source

Measuring the Hall Effect in Hysteretic Materials

open access: yesAdvanced Materials, EarlyView.
The authors highlight common pitfalls in measuring the Hall effect: in hysteretic magnets, improper data processing can create signals that look exotic but are not real. This Perspective explains the origin of these artifacts and presents practical measurement strategies that help researchers identify reliable Hall responses in complex magnetic ...
Jaime M. Moya   +6 more
wiley   +1 more source

Signatures of malaria vaccine efficacy in ageing murine immune memory.

open access: yes, 2014
Malaria transmission occurs by mosquito bite. Thereafter, Plasmodium sporozoites specifically invade the liver, where they develop into thousands of merozoites that initiate blood-stage infection and clinical malaria.
Kooij, TWA   +12 more
core   +1 more source

Ferroelectric Dynamic‐Field‐Driven Nucleation and Growth Model for Predictive Materials‐To‐Circuit Co‐Design

open access: yesAdvanced Materials, EarlyView.
This study presents a compact dynamic‐field‐driven nucleation and growth (DFNG) model that captures ferroelectric switching behavior under arbitrary voltage waveforms. It enables extraction of time‐dependent domain wall velocity and growth dimensionality, which can then be extended to device‐level modeling.
Yi Liang   +10 more
wiley   +1 more source

Simple Synthesis of Entropy Stabilized Oxides Single Crystal Films

open access: yesAdvanced Materials Interfaces, EarlyView.
Diffusion‐controlled enables the creation of a single‐crystal thin film of Entropy‐stabilized oxides (ESO). ABSTRACT Entropy‐stabilized oxides (ESO) have emerged in the last decade as a new class of metastable materials with promising functional properties.
Antoine Raison   +6 more
wiley   +1 more source

Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients

open access: yesAdvanced Robotics Research, EarlyView.
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni   +4 more
wiley   +1 more source

Distinct degree of cortical actin polymerization in naïve and memory CD4+ T cells.

open access: yes, 2013
Resting CD4+ T cells were purified from peripheral blood by negative depletion. Surface expression of CD45RA differentiated between naïve (CD45RA+) and memory (CD45RA-) CD4+ T cells.
Ester Ballana (23800)   +4 more
core   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

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