Results 51 to 60 of about 7,991,483 (301)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Changes in Chloride Cell Abundance, Na+,K+-ATPase Immunolocalization and Activity in the Gills of Golden Grey Mullet, Liza Aurata, Fry During Adaptation to Differend Salinities [PDF]

Cell Journal, 2009
Objective: Changes in chloride cell abundance, Na+, K+-ATPase immunolocalizationand activity were investigated in the gills of the golden grey mullet, Liza aurata, fry acclimatedto freshwater (FW) and different salinities (12‰, 36‰ and 46‰).Materials and
Saber Khodabandeh, Mohsen Shahriari Moghaddam, Behroz Abtahi   +2 more
doaj  

Comparative physiological and biochemical mechanisms of salt tolerance in five contrasting highland quinoa cultivars

BMC Plant Biology, 2020
Background Chenopodium quinoa Willd., a halophytic crop, shows great variability among different genotypes in response to salt. To investigate the salinity tolerance mechanisms, five contrasting quinoa cultivars belonging to highland ecotype were ...
Zhi-Quan Cai, Qi Gao
doaj   +1 more source

Is salinity the main ecological factor that influences foliar nutrient resorption of desert plants in a hyper-arid environment?

BMC Plant Biology, 2020
Background Soil salinity is a major abiotic constraint to plant growth and development in the arid and semi-arid regions of the world. However, the influence of soil salinity on the process of nutrient resorption is not well known.
Lilong Wang, Xinfang Zhang, Shijian Xu
doaj   +1 more source

Mineral nutrient composition in leaf and root tissues of fifteen polyembryonic mango genotypes, grown under varying levels of salinity

Journal of Horticultural Sciences, 2021
Mango (Mangifera indica L.) is a salt sensitive crop and its cultivation in salt affected area is declining day by day. There is a need to find out the rootstocks to sustain under saline conditions which can be used for commercial cultivation of superior
P K Nimbolkar, Reju M Kurian, L. R. Varalakshmi, K. K. Upreti, R. H. Laxman, D. Kalaivanan   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Na+ compartmentalization related to salinity stress tolerance in upland cotton (Gossypium hirsutum) seedlings [PDF]

Scientific Reports, 2016
AbstractThe capacity for ion compartmentalization among different tissues and cells is the key mechanism regulating salt tolerance in plants. In this study, we investigated the ion compartmentalization capacity of two upland cotton genotypes with different salt tolerances under salt shock at the tissue, cell and molecular levels. We found that the leaf
Zhen Peng, Shoupu He, Junling Sun, Zhaoe Pan, Wenfang Gong, Yanli Lu, Xiongming Du   +6 more
openaire   +2 more sources

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source