Results 71 to 80 of about 160,093 (303)
Evaporites and the salinity of the ocean during the Phanerozoic: Implications for climate, ocean circulation and life [PDF]
, 2005 A compilation of data on volumes and masses of evaporite deposits is used as the basis for reconstruction of the salinity of the ocean in the past.
Balukhovsky, A. N. +5 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Changes in Chloride Cell Abundance, Na+,K+-ATPase Immunolocalization and Activity in the Gills of Golden Grey Mullet, Liza Aurata, Fry During Adaptation to Differend Salinities [PDF]
Cell Journal, 2009 Objective: Changes in chloride cell abundance, Na+, K+-ATPase immunolocalizationand activity were investigated in the gills of the golden grey mullet, Liza aurata, fry acclimatedto freshwater (FW) and different salinities (12‰, 36‰ and 46‰).Materials and
Saber Khodabandeh +2 more
doaj
Spring and surface water quality of the Cyprus ophiolites [PDF]
, 2002 A survey of surface, spring and borehole waters associated with the ophiolite rocks of Cyprus shows five broad water types (1) Mg-HCO3, (2) Na-SO4-Cl-HCO3, (3) Na-Ca-Cl-SO4-OH-CO3, (4) Na-Cl-SO4 and (5) Ca-SO4.
Neal, C., Shand, P.
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Modelling start-up performance of anaerobic digestion of saline-rich macro-algae [PDF]
, 2014 Some of the key factors affecting the adaptation of anaerobic digestion processes to increasing levels of salinity were determined in batch tests using brown seaweed as a feedstock.
Akunna, Joseph C., Hierholtzer, Anthony
core +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Plants, 2022 Salinity affects the yield and quality of oilseed crops. The effects of a single foliar application of solutions with different concentrations (0, 30, 60 or 90 µM) of melatonin (MEL) to camelina (Camelina sativa) plants grown in soil in a greenhouse and ...
Mohammad Reza Forozan Bakyani +4 more
doaj +1 more source
Molecular mechanisms of adaptation of the moderately halophilic bacterium Halobacillis halophilus to its environment [PDF]
, 2013 The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately halophilic bacterium that grows between 0.4 and 3 M NaCl by accumulating both chloride and ...
Hänelt, Inga, Müller, Volker
core +2 more sources