Results 151 to 160 of about 155,744 (263)

ACMG/AMP‐Based Variant Classification of a Novel HBA2 Variant (HBA2: C.297del, Hb Taiping) in Compound Heterozygosity With Hb Adana (HBA2:C.179G>A) Causing Non‐Deletional Hb H Disease

International Journal of Laboratory Hematology, Volume 48, Issue 2, Page 458-465, April 2026.
ABSTRACT Background Accurate classification of novel globin gene variants is critical for the diagnosis and management of thalassaemia. The adaptation of ACMG/AMP guidelines for globin genes represents an important step toward standardising variant interpretation and enhancing clinical utility in the field.
Norafiza Mohd Yasin, Suguna Somasundram, Syahzuwan Hassan, Nur Aisyah Aziz, Faidatul Syazlin Abdul Hamid, Ezzanie Suffya Zulkefli, Nor Nazuha Mohamad, Chin Ming Lee, Mohd Nazif Darawi, Thessalia Papasavva, Coralea Stephanou, Petros Kountouris, Sandra J. G. Arkesteijn, Tamara Koopman, Cornelis L. Harteveld   +14 more
wiley   +1 more source

Defense Systems and Prophage Detection in Streptococcus mutans Strains

Molecular Oral Microbiology, Volume 41, Issue 2, Page 57-68, April 2026.
ABSTRACT Although the species is extensively studied, limited data are available on antiphage defense systems (APDSs) in Streptococcus mutans. The present study aimed to explore the diversity and the occurrence of APDSs and to search for prophages in the genomes of clinical isolates of S. mutans using bioinformatics tools.
Olivier Claisse, Cas Mosterd, Claire Le Marrec, Johan Samot   +3 more
wiley   +1 more source

Laurdan: Clarifying Photophysics and Advancing the Characterization of Extracellular Vesicles

ChemPhysChem, Volume 27, Issue 5, 13 March 2026.
Biophysical properties of extracellular vesicles (EVs) reflect their composition and membrane organization. We introduce a novel approach using time‐resolved emission spectra (TRES) phasor analysis of the polarity‐sensitive probe Laurdan to characterize membranes with complex compositions.
Petra Riegerová, Mariana Amaro, Peter Kapusta, Antonín Vlček, Martin Smolko, Karel Souček, Vendula Pospíchalová, Martin Hof, Šárka Pokorná   +8 more
wiley   +1 more source

Predictive value of matrix metalloproteinase-9 combined with magnetic resonance spectroscopy for delayed cerebral edema after spontaneous intracerebral hemorrhage. [PDF]

Front Physiol
Sun J, Chen L.
europepmc   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study establishes an integrated platform combining high‐throughput screening (STEM‐seq) and AI‐guided design (BaseSearch) to develop compact transcriptional enhancers in crops. We identified thousands of functional short enhancers (60–80 bp) across four species, with the strongest showing 46.3‐fold activation.
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Neurometabolics of the anterior cingulate cortex (ACC) in major depressive disorder (MDD): A systematic review and meta-analysis. [PDF]

Neuroimage Clin
White AJ, Robinson JL, Wilson AE, Reid MA.   +3 more
europepmc   +1 more source

Low‐intensity prescribed fire has no immediate impact on soil physical and chemical properties or enzymatic activity in the Post Oak Savanna ecoregion, Texas, USA

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract The historic development of the Post Oak Savanna ecoregion in Texas, USA, was shaped by natural wildfires. However, wildfire suppression has caused an increase in encroaching woody species. To address this issue, land management strategies incorporate prescribed fire (PF) for the control of encroaching species.
Kathryn L. Watson, Jordan E. Gignac, Alejandro Atenas Navarrete, Leila Joharzadeh, Bismark Osei, Dinesh Phuyal, Chiranjibi Poudyal, Mingxiu Wang, Larissa Watkins, Opeyemi Alabi, Siddhartha Shankar Bhattacharyya, Nicholas Boogades, Achla Jha, Deepa Khadka, Dallas M. Williams, A. Peyton Smith, Briana M. Wyatt   +16 more
wiley   +1 more source

Application of untargeted plasma metabolomics and machine learning to construct a diagnostic model for hypertrophic cardiomyopathy: a case-control study. [PDF]

Metabolomics
Li R, Wang B, Shan B, Sun M, Ta S, Zhao J, Kang N, Yang F, Yuan Y, Li X, Wang H, Fan L, Zheng H, Wang J, Liu L.   +14 more
europepmc   +1 more source

Machine Learning Approach for Differentiation of Pheochromocytoma from Adrenocortical Cancer and Non-Functioning Adrenal Adenomas. [PDF]

Life (Basel)
Nurkhabinov T, Ilovayskaya I, Lugovskaya A, Popov V, Nefedova L.   +4 more
europepmc   +1 more source

Clinal Variation in Reproductive Modes and Offspring Body Condition Across a Contact Zone of a Bimodal Viviparous Salamander

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We examined clinal gradients in reproductive modes and associated offspring body condition across a hybrid zone between two bimodal viviparous subspecies of Salamandra salamandra. We found a clear cline in reproductive modes, with pure modes at the extremes and mixed modes in central populations.
Clara Figueiredo‐Vázquez, Lucía Alarcón‐Ríos, Guillermo Velo‐Antón   +2 more
wiley   +1 more source