ABSTRACT Chronic kidney disease (CKD) is common and a major contributor to increased morbidity and early mortality in people with sickle cell anemia (SCA). Urine albumin‐to‐creatinine ratio (uACR) is recommended to identify patients with SCA‐related CKD but its utility in predicting long‐term kidney dysfunction remains unclear in this patient ...
Pablo Bartolucci +12 more
wiley +1 more source
Decadelong low basal ganglia NAA/tCr from elevated tCr supports ATP depletion from mitochondrial dysfunction and neuroinflammation in Gulf War illness. [PDF]
Cheshkov S +8 more
europepmc +1 more source
Female‐biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu
Abstract INTRODUCTION The locus coeruleus (LC) is an early site of Alzheimer's disease (AD) pathology, yet the role of brainstem astrocytes in early, sex‐dependent vulnerability remains unclear. METHODS In 2‐ to 3‐month‐old APP/PS1 mice, we combined in vivo proton magnetic resonance spectroscopy (MRS) of the brainstem with region‐resolved molecular ...
Srishti Kushwaha +4 more
wiley +1 more source
Risk factors for atopic and non-atopic asthma in school-age children from high-income and low- and middle-income countries. [PDF]
Rutter CE +16 more
europepmc +1 more source
Blood‐Based Lead Biomarkers and Sarcopenia Indicators in Older Adults
ABSTRACT Background Chronic exposure to low levels of lead (Pb) remains a widespread public health issue, especially among older adults. While its neurotoxic and cardiovascular effects are well recognized, its potential role in accelerating age‐related musculoskeletal decline is less understood.
Aida Koni +15 more
wiley +1 more source
Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology. [PDF]
Vicencio J +5 more
europepmc +1 more source
Effects of GA3, NAA and PCPA on the Fruit Drop Rate and Quality of Ziziphus jujuba lZhanshanmizaor [PDF]
Yang Wang +3 more
openalex +1 more source
The Role of MRI in Debunking the Fallacy of “Mild” Traumatic Brain Injury
ABSTRACT Mild traumatic brain injury (mTBI) is a prevalent yet often overlooked public health concern due to the absence of detectable abnormalities on CT or conventional MRI scans. Approximately 18.3%–31.3% of mTBI patients experience persistent symptoms 3–6 months post‐injury, despite normal imaging results, making diagnosis and treatment challenging.
Xingye Chen +3 more
wiley +1 more source
The effects of gut microbiota-derived short-chain fatty acids (SCFAs) on human colon cancer cells: An in vitro study. [PDF]
Darabi S +4 more
europepmc +1 more source
Comprehensive Phytohormone Analysis Reveals the Roles of Auxin, Cytokinin, and Gibberellin in Enhancing Seed Germination and Growth of <i>Chimonobambusa utilis</i>. [PDF]
Zhao W, Ai S, Yuan H, Lv M, Lin S.
europepmc +1 more source

