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Costs of First-Line Treatment With FOLFIRINOX, Modified FOLFIRINOX, and Gemcitabine With Nab-Paclitaxel in Metastatic Pancreatic Ductal Adenocarcinoma. [PDF]
Dennen S +4 more
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Phase IB trial of high dose ascorbic acid + nab-paclitaxel + cisplatin + gemcitabine in patients with untreated metastatic pancreatic cancer. [PDF]
Jameson GS +16 more
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Noninvasive Computed Tomography-Based Quantification of Tumor Fibrosis Predicts Pancreatic Cancer Response to Gemcitabine/Nab-Paclitaxel. [PDF]
Yang Q +19 more
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Nab-Paclitaxel related cystoid macular edema.
La Clinica terapeutica, 2022Nab-paclitaxel is a chemotherapeutic drug used to treat various solid malignant tumors. It was conceived with a solvent free formulation to overcome toxicity events and hypersensitivity reactions associated with paclitaxel. However, it still carries ocular adverse effects.
Di Pippo, M +4 more
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Bulletin du Cancer, 2015
Resume Le paclitaxel est classiquement utilise dans un vaste eventail d’indications en oncologie. Le nab-paclitaxel est synthetise par un processus d’homogeneisation a haute pression du paclitaxel en presence d’albumine humaine et il a ete initialement developpe pour diminuer la toxicite generalement associee au cremophor du paclitaxel soluble et ...
Daniel Lopez-Trabada Ataz +2 more
openaire +1 more source
Resume Le paclitaxel est classiquement utilise dans un vaste eventail d’indications en oncologie. Le nab-paclitaxel est synthetise par un processus d’homogeneisation a haute pression du paclitaxel en presence d’albumine humaine et il a ete initialement developpe pour diminuer la toxicite generalement associee au cremophor du paclitaxel soluble et ...
Daniel Lopez-Trabada Ataz +2 more
openaire +1 more source
Nab-paclitaxel: A flattering facelift
Critical Reviews in Oncology/Hematology, 2014The application of nanotechnology in oncology has increased the efficacy and efficiency of some cytotoxic agents. The paradigm in this field is nab-paclitaxel, a soluble form of paclitaxel that is linked to albumin nanoparticles. The development of nanotechnology as a delivery system for paclitaxel has provided better pharmacokinetic and ...
A, Viúdez +5 more
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Cystoid macular edema induced by nab-paclitaxel
Breast Cancer, 2012Cystoid macular edema (CME) is a rare complication of taxane-based chemotherapy. We encountered a patient who developed CME during treatment with nab-paclitaxel for metastatic breast cancer. Early detection of this disease enables continuation of appropriate treatment without reducing the quality of life for patients with end-stage disease.
Yuko, Tanaka +4 more
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Nab-paclitaxel in patients with metastatic melanoma
Expert Review of Anticancer Therapy, 2015Cutaneous melanoma is one of the most aggressive and resistant malignancies in humans. Until recently, progress in the treatment of metastatic melanoma remained dormant for nearly two decades. However, recent advances in immune and targeted therapeutic approaches have led to dramatic and paradigm-shifting advances in the management of metastatic ...
Roberto A, Leon-Ferre +1 more
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Bulletin du cancer, 2015
Paclitaxel is conventionally used in a wide range of oncology indications. Nab-paclitaxel is synthesized by a process of high pressure homogenization of paclitaxel in the presence of human albumin and it was originally developed to reduce the toxicity usually associated with cremophor in soluble paclitaxel and to increase its penetration in tumor ...
Daniel, Lopez-Trabada Ataz +2 more
openaire +1 more source
Paclitaxel is conventionally used in a wide range of oncology indications. Nab-paclitaxel is synthesized by a process of high pressure homogenization of paclitaxel in the presence of human albumin and it was originally developed to reduce the toxicity usually associated with cremophor in soluble paclitaxel and to increase its penetration in tumor ...
Daniel, Lopez-Trabada Ataz +2 more
openaire +1 more source
Metabolism of the taxanes including nab-paclitaxel
Expert Opinion on Drug Metabolism & Toxicology, 2014The classical taxanes (paclitaxel, docetaxel), the newer taxane cabazitaxel and the nanoparticle-bound nab-paclitaxel are among the most widely used anticancer drugs. Despite years of research, the optimal dosing regimen (weekly vs 3-weekly) and optimal dose is still controversial, as is the value of pharmacological personalization of taxane dosing ...
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