Results 31 to 40 of about 49,721 (234)
PLoS ONE, 2021 We developed a novel preparative method for nanoparticle albumin-bound (nab) paclitaxel with high drug loading, which was based on improved paclitaxel solubility in polyethylene glycol (PEG) and self-assembly of paclitaxel in PEG with albumin powders ...
Yue Gao +15 more
doaj +1 more source
Superior antitumor activity of nanoparticle albumin-bound paclitaxel in experimental gastric cancer. [PDF]
PLoS ONE, 2013 Gastric cancer is the second common cause of cancer related death worldwide and lacks highly effective treatment for advanced disease. Nab-paclitaxel is a novel microtubule-inhibitory cytotoxic agent that has not been tested in gastric cancer as of yet ...
Changhua Zhang +4 more
doaj +1 more source
A case of hemorrhagic cystitis caused by nab-paclitaxel [PDF]
International Cancer Conference Journal, 2016 Nab-paclitaxel (nab-PTX) is a nanoparticle albumin-bound paclitaxel and, as such, is free of solvents like ethanol and polyoxyethylene castor oil. The absence of solvents from this formulation has several practical advantages: it has a shorter infusion time, it negates the need for premedications for hypersensitivity reactions, and it can be ...
Emika, Ichioka +9 more
openaire +2 more sources
Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma
BMC Cancer, 2020 Background The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing.
Zhichao Tian +7 more
doaj +1 more source
Therapeutic Advances in Medical Oncology, 2020 Background: The effectiveness of atezolizumab plus nab-paclitaxel for advanced triple-negative breast cancer (TNBC) has been demonstrated. We aimed to evaluate its cost-effectiveness on advanced TNBC from the US payer perspective. Methods: A Markov model
Bin Wu, Fei Ma
doaj +1 more source
Thoracic Cancer, 2020 Background Previous trials have suggested that elderly patients with non‐small‐cell lung cancer (NSCLC) could benefit from nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel). Real‐world data on the elderly Chinese population are lacking.
Shuhang Wang +12 more
doaj +1 more source
Frontiers in Public Health, 2021 Purpose: The IMpassion130 trial demonstrated the efficacy of adding atezolizumab to paclitaxel for advanced or metastatic triple-negative breast cancer (TNBC).
Xiaoyan Liu +4 more
doaj +1 more source
Translational Oncology, 2018 Esophageal adenocarcinoma (EAC) is the fastest growing cancer in the western world and the overall 5 year survival rate of EAC is below 20%. Most patients with EAC present with locally advanced or widespread metastatic disease, where current treatment is
Md Sazzad Hassan +6 more
doaj +1 more source
Dermatology Practical & Conceptual, 2015 Background: Taxanes [paclitaxel, nab-paclitaxel (Abraxane, Celgene Corp, USA), and docetaxel]—used in the treatment of lung, breast, and head and neck cancers—have been associated with cutaneous adverse effects, including photodermatoses.
Bryce D. Beutler, Philip R. Cohen
doaj +1 more source
Clinical efficacy of nab-paclitaxel in patients with metastatic pancreatic cancer [PDF]
, 2018 Purpose: Pancreatic carcinoma is the neoplasia with the major mortality, and main standard treatments in this cancer increase survival but do not lead to complete recovery of the patient. The aim of this study was to evaluate the efficacy of Abraxane® (
GRISTINA, Valerio +9 more
core +1 more source