Results 31 to 40 of about 55,457 (267)

A case of hemorrhagic cystitis caused by nab-paclitaxel [PDF]

open access: yesInternational Cancer Conference Journal, 2016
Nab-paclitaxel (nab-PTX) is a nanoparticle albumin-bound paclitaxel and, as such, is free of solvents like ethanol and polyoxyethylene castor oil. The absence of solvents from this formulation has several practical advantages: it has a shorter infusion time, it negates the need for premedications for hypersensitivity reactions, and it can be ...
Emika, Ichioka   +9 more
openaire   +2 more sources

A novel preparative method for nanoparticle albumin-bound paclitaxel with high drug loading and its evaluation both in vitro and in vivo.

open access: yesPLoS ONE, 2021
We developed a novel preparative method for nanoparticle albumin-bound (nab) paclitaxel with high drug loading, which was based on improved paclitaxel solubility in polyethylene glycol (PEG) and self-assembly of paclitaxel in PEG with albumin powders ...
Yue Gao   +15 more
doaj   +1 more source

Efficacy and Safety of Albumin-Bound Paclitaxel Compared to Docetaxel as Neoadjuvant Chemotherapy for HER2-Negative Breast Cancer

open access: yesFrontiers in Oncology, 2022
BackgroundNanoparticle albumin-bound paclitaxel (nab-paclitaxel) as neoadjuvant chemotherapy (NAC) for breast cancer remains controversial. We conducted a retrospective study to compare the efficacy and safety of nab-paclitaxel with those of docetaxel as
Zhi-Dong Lv   +7 more
doaj   +1 more source

Superior antitumor activity of nanoparticle albumin-bound paclitaxel in experimental gastric cancer. [PDF]

open access: yesPLoS ONE, 2013
Gastric cancer is the second common cause of cancer related death worldwide and lacks highly effective treatment for advanced disease. Nab-paclitaxel is a novel microtubule-inhibitory cytotoxic agent that has not been tested in gastric cancer as of yet ...
Changhua Zhang   +4 more
doaj   +1 more source

Neoadjuvant nab-paclitaxel in the treatment of breast cancer [PDF]

open access: yesBreast Cancer Research and Treatment, 2016
Neoadjuvant chemotherapy has the advantage of converting unresectable breast tumors to resectable tumors and allowing more conservative surgery in some mastectomy candidates. Chemotherapy agents, including taxanes, which are recommended in the adjuvant setting, are also considered in the neoadjuvant setting. Here, we review studies of nab-paclitaxel as
Ueno, Naoto T., Mamounas, Eleftherios P.
openaire   +2 more sources

Albumin-bound paclitaxel and gemcitabine combination therapy in soft tissue sarcoma

open access: yesBMC Cancer, 2020
Background The evidence that albumin-bound paclitaxel (nab-paclitaxel) is safe and efficacious for the treatment of many types of malignant tumors is continuously increasing.
Zhichao Tian   +7 more
doaj   +1 more source

Retrospective analysis of the effectiveness and tolerability of nab‐paclitaxel in Chinese elderly patients with advanced non‐small‐cell lung carcinoma

open access: yesThoracic Cancer, 2020
Background Previous trials have suggested that elderly patients with non‐small‐cell lung cancer (NSCLC) could benefit from nanoparticle albumin‐bound paclitaxel (nab‐paclitaxel). Real‐world data on the elderly Chinese population are lacking.
Shuhang Wang   +12 more
doaj   +1 more source

Atezolizumab Plus Chemotherapy vs. Chemotherapy in Advanced or Metastatic Triple-Negative Breast Cancer: A Cost-Effectiveness Analysis

open access: yesFrontiers in Public Health, 2021
Purpose: The IMpassion130 trial demonstrated the efficacy of adding atezolizumab to paclitaxel for advanced or metastatic triple-negative breast cancer (TNBC).
Xiaoyan Liu   +4 more
doaj   +1 more source

Cost-effectiveness of adding atezolizumab to first-line chemotherapy in patients with advanced triple-negative breast cancer

open access: yesTherapeutic Advances in Medical Oncology, 2020
Background: The effectiveness of atezolizumab plus nab-paclitaxel for advanced triple-negative breast cancer (TNBC) has been demonstrated. We aimed to evaluate its cost-effectiveness on advanced TNBC from the US payer perspective. Methods: A Markov model
Bin Wu, Fei Ma
doaj   +1 more source

Superior Therapeutic Efficacy of Nanoparticle Albumin Bound Paclitaxel Over Cremophor-Bound Paclitaxel in Experimental Esophageal Adenocarcinoma

open access: yesTranslational Oncology, 2018
Esophageal adenocarcinoma (EAC) is the fastest growing cancer in the western world and the overall 5 year survival rate of EAC is below 20%. Most patients with EAC present with locally advanced or widespread metastatic disease, where current treatment is
Md Sazzad Hassan   +6 more
doaj   +1 more source

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