Results 101 to 110 of about 6,475,937 (327)

A Contribution of Beef to Human Health: A Review of the Role of the Animal Production Systems [PDF]

, 2016
Meat and meat products constitute important source of protein, fat, and several functional compounds. Although beef consumption may implicate possible negative impacts on human health, its consumption can also contribute to human health.
Chamorro, Monica Viviana, Cunzolo, Sebastian Abel, Godoy, Maria Fernanda, Grigioni, Gabriela Maria, Messina, Valeria Marisa, Paschetta, María Fernanda, Pazos, Adriana Alejandra, Pighín, Darío Gabriel, Pordomingo, Anibal Javier   +8 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Theoretical and experimental study of a new thiosulfonate derivative: Methyl trifluoromethanethiosulfonate, CF3SO2SCH3. Conformational transferability in CX3SO2S-R compounds [PDF]

, 2017
Methyl trifluoromethanethiosulfonate, CF3SO2SCH3, was synthesized and characterized by 13C NMR, 19F NMR, and vibrational spectroscopy. This structural study was supported by MP2 and DFT (B3LYP and MPW1PW91) calculations, which revealed a strong ...
Ben Altabef, Aída, Contreras Aguilar, Elizabeth, Defonsi Lestard, Maria Eliana, Galván, Jorge Edgardo, Tuttolomondo, María Eugenia, Ulic, Sonia Elizabeth   +5 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Comparing the performance of two structural indicators for different water models while seeking for connections between structure and dynamics in the glassy regime [PDF]

, 2019
In this work, we compare the performance of two structural indicators based on the degree of translational order up to the second coordination shell in three water models: SPC/E, TIP4P/2005, and TIP5P.
Alejandro R. Verde, Debenedetti P. G., Gustavo A. Appignanesi, Joan Manuel Montes de Oca, Laureano M. Alarcón, Sebastián R. Accordino   +5 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Understanding the structure and reactivity of NiCu nanoparticles: An atomistic model [PDF]

, 2017
The structure of bimetallic NiCu nanoparticles (NP) is investigated as a function of their composition and size by means of Lattice MonteCarlo (LMC) and molecular dynamics (MD) simulations.
Belletti, Gustavo Daniel, Glukhov, D. V., Nazmutdinov, Renat, Quaino, Paola Monica, Santos, Elizabeth del Carmen, Schmickler, Wolfgang, Shermukhamedov, S. A.   +6 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Asia- Pacífico en la Estrategia de Seguridad Nacional 2013

Revista UNISCI, 2014
A pesar de que la Estrategia de Seguridad Nacional incluye Asia-Pacífico entre los entornos estratégicos considerados como prioritarios para España, un análisis más pausado del documento revela que, en realidad, la importancia que se otorga a la región ...
Gracia Abad
doaj  

Molecular Networks in Dynamic Multilevel Systems [PDF]

, 2018
Dynamic multilevel systems can be assembled from molecular building blocks through two or more reversible reactions that form covalent bonds. Molecular networks of dynamic multilevel systems can exhibit different connectivities between nodes.
Cabezudo, Ignacio, Escalante, Andrea Marta, Furlan, Ricardo Luis Eugenio, Martinez Amezaga, Maitena, Orrillo, Alfredo Gastón   +4 more
core   +1 more source