Results 41 to 50 of about 3,802,167 (299)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Lecturas de Economía, 2015 Con base en un modelo probit ordenado generalizado se ofrece evidencia estadística en favor de la tesis de economía política. Esta tesis sostiene que los partidos de gobierno en democracias precarizadas por grupos de poder, en las cuales el narcotráfico ...
Andrés Cendales +2 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Competitividade das nações: análise da métrica utilizada pelo World Economic Forum
RAE: Revista de Administração de Empresas, 2012 A competitividade das nações é assunto relevante aos tomadores de decisão quando se trata da escolha do país que poderá render melhores resultados aos investimentos.
Luciano Castro de Carvalho +2 more
doaj
Regimento interno do Conselho Nacional do Trabalho [PDF]
, 1944 Da organização do Conselho Nacional do Trabalho -- Da distribuição dos processos -- Da pauta de julgamento -- Das sessões -- Dos acórdãos -- Das exceções -- Dos conflitos de jurisdição -- Da interposição dos recursos -- Das consultas e projetos de leis e
Conselho Nacional do Trabalho (Brasil) (CNT)
core
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Fortalecimiento de la escuela nacional de agricultura "Roberto Quiñónez".
, 2013 El 28 de agosto de 1956 fue inaugurada La Escuela Nacional de Agricultura, con el imperioso objetivo de formar profesionales en el agro, con capacidades de impulsar el desarrollo agropecuario nacional, que se estaba viviendo entonces; mejorando la ...
Consejo Nacional de Ciencia y Tecnología (CONACYT)
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source