Results 21 to 30 of about 3,802,167 (299)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Supporting Survivor‐Centered Care Through Digital Health Integration
Pediatric Blood &Cancer, EarlyView.ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak +15 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 1954 Reseña histórica del Museo Nacional. Secciones: Salón de la Colonia, Salón de la Independencia, Salón de la Gran Colombia, Salón de la República, Salón de Ciencias Naturales y Etnología, Salón de Variedades.
Universidad Nacional, Colombia
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
La seguridad marítima en la Estrategia de Seguridad Nacional 2013
Revista UNISCI, 2014 La Estrategia de Seguridad Nacional no parece conceder a la seguridad marítima la importancia que debería si se tiene en cuenta tanto la posición geográfica de España como la relevancia que tiene el mar en los intercambios comerciales de nuestro país. En
Gracia Abad
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
ANÁLISIS DE LAS FALACIAS EN TORNO A LA TEORÍA DE LA SOBERANÍA NACIONAL (O POPULAR)
Prolegómenos, 2017 El presente artículo trata de aportar una crítica lógica a la teoría de la soberanía nacional (o popular). Mediante los métodos histórico y filosófico se analizan las falacias, cuestionando una teoría política nacida de la Revolución francesa y que ...
Luis-Tomás Zapater Espí
doaj
Instituto nacional de radium [PDF]
, 1954 Reseña histórica del Instituto: "El Instituto Nacional de Radium es un centro de investigación científica destinado a la asistencia social para estudiar y tratar el cáncer y además entidades patológicas tratables por los mismos procedimientos del cáncer.
Universidad Nacional, Colombia
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