Results 101 to 110 of about 1,801,950 (296)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Cloning and characterization of gene encoding a Mn-containing superoxide dismutase in Eutrema halophilum

Biologia Plantarum, 2014
A gene encoding Mn-containing superoxide dismutase (Mn-SOD), designated as ThMSD, was cloned from salt cress (Eutrema halophilum) by reverse transcriptase - polymerase chain reaction (RT-PCR) and rapid amplification of cDNA ends (RACE).
X. J. Xu, Y. J. Zhou, D. T. Ren, H. H. Bu, J. C. Feng, G. Y. Wang   +5 more
doaj   +1 more source

Reactions of chromium with gaseous NaCl in an oxygen environment [PDF]

Target collection techniques and high pressure mass spectrometric sampling have been used to study the formation of volatile chromium-containing species in the reaction of Cr2O3 with O2 and NaCl gases.
Fryburg, G. C., Kohl, F. J., Stearns, C. A.   +2 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Differential growth responses to sodium salts involve different abscisic acid metabolism and transport in Prosopis strombulifera

Biologia Plantarum, 2014
In this work, the response of the halophytic shrub Prosopis strombulifera to lowering an osmotic potential (Ψo) to -1.0, -1.9, and -2.6 MPa generated by NaCl, Na2SO4, and the iso-osmotic combination of them was studied at 6, 12, and 24 h after reaching ...
A. Llanes, O. Masciarelli, R. Ordóñez, M. I. Isla, V. Luna   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Identification of a C2H2-type zinc finger gene family from Eucalyptus grandis and its response to various abiotic stresses

Biologia Plantarum, 2014
C2H2-type zinc finger proteins belong to a major family of transcription factors that play a crucial role in plant stress responses. In this study, seven C2H2-type zinc finger genes (EgrZFP1-7) in Eucalyptus grandis were cloned using the RACE PCR method.
S. Wang, X. L. Wei, L. J. Cheng, Z. K. Tong   +3 more
doaj   +1 more source

Salt crystallization dynamics in building rocks: a 4D study using laboratory X-ray micro-CT [PDF]

, 2015
We employ laboratory X-ray micro-computed tomography (μCT) during climate-controlled salt weathering experiments to acquire data on the kinetics of drying and salt precipitation and the distribution of crystals within the pore space of Mšené sandstone ...
Boone, Marijn, Boone, Matthieu, Cnudde, Veerle, De Kock, Tim, De Miranda, Stefano, Derluyn, Hannelore, Desarnaud, Julie, Molari, Lisa, Peetermans, Steven, Shahidzadeh, Noushine   +9 more
core  

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Improved salt tolerance and delayed leaf senescence in transgenic cotton expressing the Agrobacterium IPT gene

Biologia Plantarum, 2012
The manipulation of cytokinin contents via Agrobacterium-mediated transformation is an efficient tool for delaying leaf senescence and improving the resistance to environmental stresses.
Y. D. Liu, Z. J. Yin, J. W. Yu, J. LI, H. L. Wei, X. L. Han, F. F. Shen   +6 more
doaj   +1 more source