Results 11 to 20 of about 71,648 (238)

Measurement of Chloroplastic NAD Kinase Activity and Whole Tissue NAD Kinase Assay [PDF]

Bio-Protocol, 2020
Nicotinamide adenine dinucleotide phosphate (NADP) synthesis requires nicotinamide adenine dinucleotide (NAD) kinase activity, substrate NAD and ATP.
Yuma Ishikawa, Maki Kawai-Yamada, Shin‐nosuke Hashida   +2 more
doaj   +4 more sources

New Chemical Probe Targeting Bacterial NAD Kinase [PDF]

Molecules, 2020
Nicotinamide adenine dinucleotide (NAD) kinases are essential and ubiquitous enzymes involved in the tight regulation of NAD/nicotinamide adenine dinucleotide phosphate (NADP) levels in many metabolic pathways.
David A. Clément, Clarisse Leseigneur, Muriel Gelin, Dylan Coelho, Valérie Huteau, Corinne Lionne, Gilles Labesse, Olivier Dussurget, Sylvie Pochet   +8 more
doaj   +4 more sources

Mitochondrial NAD kinase in health and disease [PDF]

Redox Biology, 2023
Nicotinamide adenine dinucleotide phosphate (NADP), a co-enzyme and an electron carrier, plays crucial roles in numerous biological functions, including cellular metabolism and antioxidation.
Ren Zhang, Kezhong Zhang
doaj   +2 more sources

Molecular properties and regulation of NAD+ kinase (NADK) [PDF]

Redox Biology, 2023
Nicotinamide adenine dinucleotide (NAD+) kinase (NADK) phosphorylates NAD+, thereby producing nicotinamide adenine dinucleotide phosphate (NADP). Both NADK genes and the NADP(H)-producing mechanism are evolutionarily conserved among archaea, bacteria ...
Shin-ichi Oka, Allen Sam Titus, Daniela Zablocki, Junichi Sadoshima   +3 more
doaj   +2 more sources

Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis [PDF]

mBio, 2023
Nicotinamide adenine dinucleotide (NAD) and its phosphorylated derivative (NADP) are essential cofactors that participate in hundreds of biochemical reactions and have emerged as therapeutic targets in cancer, metabolic disorders, neurodegenerative ...
Ritu Sharma, Travis E. Hartman, Tiago Beites, Jee-Hyun Kim, Hyungjin Eoh, Curtis A. Engelhart, Linnan Zhu, Daniel J. Wilson, Courtney C. Aldrich, Sabine Ehrt, Kyu Young Rhee, Dirk Schnappinger   +11 more
doaj   +2 more sources

LncRNA like NMRK2 mRNA functions as a key molecular scaffold to enhance mitochondrial respiration of NONO-TFE3 rearranged renal cell carcinoma in an NAD⁺ kinase-independent manner. [PDF]

J Exp Clin Cancer Res, 2023
Chen Y, Lu Y, Yang L, Ma W, Dong Y, Zhou S, Liu N, Gan W, Li D.   +8 more
europepmc   +3 more sources

NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes. [PDF]

Elife, 2022
Leseigneur C, Boucontet L, Duchateau M, Pizarro-Cerda J, Matondo M, Colucci-Guyon E, Dussurget O.   +6 more
europepmc   +2 more sources

Evaluating the effects of synthetic POM cycles and NAD+ kinase expression on fatty alcohol production in Saccharomyces cerevisiae. [PDF]

PLoS One
McNeil BA, Khalifa C, Krishnan A, Stuart DT.   +3 more
europepmc   +2 more sources

Cryo-EM structure and regulation of human NAD kinase. [PDF]

Sci Adv
Praharaj PP, Li Y, Mary C, Soflaee MH, Ryu K, Kim D, Tran DH, Dey T, Tom HJ, Rion H, Gelin M, Lemoff A, Zacharias LG, Patricio JS, Mathews TP, Chen Z, Lionne C, Hoxhaj G, Labesse G.   +18 more
europepmc   +2 more sources

Dihydronicotinamide Riboside Is a Potent NAD+ Precursor Promoting a Pro-Inflammatory Phenotype in Macrophages

Frontiers in Immunology, 2022
Nicotinamide adenine dinucleotide (NAD) metabolism plays an important role in the regulation of immune function. However, a complete picture of how NAD, its metabolites, precursors, and metabolizing enzymes work together in regulating immune function and
Claudia C. S. Chini, Claudia C. S. Chini, Thais R. Peclat, Lilian S. Gomez, Julianna D. Zeidler, Gina M. Warner, Sonu Kashyap, Sonu Kashyap, Delaram Z. Mazdeh, Faisal Hayat, Faisal Hayat, Marie E. Migaud, Marie E. Migaud, Aneel Paulus, Asher A. Chanan-Khan, Asher A. Chanan-Khan, Eduardo N. Chini, Eduardo N. Chini   +17 more
doaj   +1 more source