Tuned by time: the role of circadian rhythms in metabolic energy sensing and chronotherapy. [PDF]
Ann MedThanuskodi Rajakumar A +1 more
europepmc +1 more source
Effect of the NAD+ Kinases Utr1, Yef1, and Pos5c on fatty alcohol production.
Bonnie A. McNeil (22331601) +3 more
openalex +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
NAD<sup>+</sup> Homeostasis and Autophagy: Integrated Control Through Nutrient Signaling in Yeast and Mammals. [PDF]
CellsMcDaniel M, Lee LH, Lin SJ.
europepmc +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
The Roles of Moonlighting Nicotinamide Mononucleotide Adenylyl Transferases in Cell Physiology. [PDF]
Int J Mol SciLee YC, Lin SJ.
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Preventive and Protective Effects of Nicotinamide Adenine Dinucleotide Boosters in Aging and Retinal Diseases. [PDF]
Int J Mol SciNoreen S, Lim SS, Lee D.
europepmc +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Draft genome and alcohol dehydrogenase dataset of thermoanaerobacter uzonensis bacterium strain AK85. [PDF]
Data BriefAbraham CA +6 more
europepmc +1 more source