Results 261 to 270 of about 73,229 (276)

NAD Kinase Is an AKT Substrate

Cancer Discovery, 2019
Abstract AKT-mediated phosphorylation of NAD kinase induces synthesis of NADP+ and NADPH.
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Compact NAD mimics as selective inhibitors of NAD kinases

2009
We have examined sequence diversity of 147 co-crystal structures of proteins utilizing NAD as a cofactor or as a substrate. Most of these proteins bind NAD in an extended conformation (e.g. the distance between the adenine 6-amino group of NAD and the nicotinamide amide carbon is 16 Å or more). However, there are clear exceptions to this general trend.
PETRELLI, Riccardo, SHAM Y. Y, CHEN L, FELCZAK, K, DI STEFANO M, MAGNI G, PANKIEWICZ K. W.   +6 more
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Immobilization of NAD Kinase

Annals of the New York Academy of Sciences, 1984
X S, Ji, H X, Li, Z Y, Yuan, S H, Liu
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PROBING BINDING REQUIREMENTS OF NAD KINASE WITH MODIFIED NAD ANALOGUES

2012
NAD kinase (NADK) catalyzes a magnesium-dependent phosphorylation of the 2′-hydroxyl group of the adenosine ribose moiety of nicotinamide adenine dinucleotide (NAD) using ATP or inorganic polyphosphates as phosphoryl donors to give NADP. There are two classes of the enzyme, one is specific for NAD+ and the other also phosphorylates NADH.
PETRELLI, Riccardo, VITA, PATRIZIA, TORQUATI, ILARIA, Krzysztof Felczak, Palmarisa Franchetti, Mario Grifantini, Michele Di Stefano, Giulio Magni, Krzysztof W. Pankiewicz, CAPPELLACCI, Loredana   +9 more
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[Thermoinactivation of NAD-kinase from rabbit liver].

Biokhimiia (Moscow, Russia), 1995
Thermal inactivation of homogeneous NAD-kinase and its partially purified preparation containing NAD-kinase in complex with glutamate dehydrogenase has been studied. The complex is more resistant to thermal inactivation in comparison with isolated NAD-kinase; its inactivation consists in irreversible dissociation preceded by a period of constant ...
G V, Afanas'eva, E R, Bulygina, V I, Telepneva   +2 more
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[Interaction of NAD-kinase with glutamate dehydrogenase].

Biokhimiia (Moscow, Russia), 1988
The formation of a NAD kinase-glutamate dehydrogenase complex was studied, using three independent methods. It was found that the polymeric form of glutamate dehydrogenase is involved in the formation of a complex with NAD kinase. Both the oligomeric and monomeric (subunit) forms of NAD kinase were shown to possess the ability to form complexes with ...
O L, Voronina, E R, Bulygina, V I, Telepneva   +2 more
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NAD+ kinase

1997
Dietmar Schomburg, Dörte Stephan
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NAD+ Kinase

2007
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[15] NAD+ kinase from sea urchin eggs

1980
Publisher Summary This chapter discusses the nicotinamide adenine dinucleotide (NAD + ) kinase from sea urchin eggs. NAD + kinase activity can be measured fluorometrically, by reducing the nicotinamide adenine dinucleotide phosphate (NADP + ) formed to NADPH, with glucose 6-phosphate and glucose 6-phosphate dehydrogenase. NAD + kinase can be stored
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NAD + mediated stabilization of NAD kinase influences NOX activity

2018
Karthikeyan Thirugnanam, Sidhartha Tan, Vivar, Jeannette Vasquez   +2 more
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