Results 321 to 330 of about 127,437 (365)

NAD+ kinase—A review

International Journal of Biochemistry, 1985
NAD+ kinase catalyzes the only (known) biochemical reaction leading to the production of NADP+ from NAD+. Most evidence indicates it is found in the cytoplasm, but reports of its presence in (other) cell bodies can not be discounted. Viewed as a protein, our knowledge of NADK composition and architecture is rudimentary.
James R. Butler, Eugene T. McGuinness
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Protein kinase C activates NAD kinase in human neutrophils

Free Radical Biology and Medicine, 2020
NAD kinase (NADK) is required for the de novo synthesis of NADP+ from NAD+. In neutrophils, NADK plays an essential role by providing sufficient levels of NADPH to support a robust oxidative burst. Activation of NADPH oxidase-2 (NOX-2) in neutrophils by stimulators of protein kinase C (PKC), such as phorbol myristate acetate (PMA), results in the rapid
François Graham, Chantal Cossette, William S. Powell, Razieh Rabani   +3 more
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Probing binding requirements of NAD kinase with modified substrate (NAD) analogues

Bioorganic & Medicinal Chemistry Letters, 2007
Synthesis of novel NAD(+) analogues that cannot be phosphorylated by NAD kinase is reported. In these analogues the C2' hydroxyl group of the adenosine moiety was replaced by fluorine in the ribo or arabino configuration (1 and 2, respectively) or was inverted into arabino configuration to give compound 3.
Laurent Bonnac, Guangyao Gao, Krzysztof Felczak, Liqiang Chen, Rashmi Pathak, Martin Kullberg, Giulio Magni, Eric M. Bennett, Steven E. Patterson, Qian Ming, Krzysztof W. Pankiewicz, Francesca Mazzola   +11 more
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Diacylglyceride kinases, sphingosine kinases and NAD kinases: distant relatives of 6-phosphofructokinases

Trends in Biochemical Sciences, 2002
Diacylglyceride kinases, sphingosine kinases, NAD kinases and 6-phosphofructokinases are thought to be related despite large evolution of their sequences. Discovery of a common signature has led to the suggestion that they possess a similar phosphate-donor-binding site and a similar phosphorylation mechanism. The substrate- and allosteric-binding sites
Labesse, Gilles, Douguet, Dominique, Assairi, Liliane, Gilles, Anne-Marie   +3 more
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THE INDUCTION OF NAD KINASE BY DDT IN TRIATOMA INFESTANS

Canadian Journal of Biochemistry, 1967
The NAD kinase (EC 2.7.1.23) from Triatoma infestans has been purified and a specific antiserum against it prepared. Immunochemical techniques have shown that the increase in the levels of NAD kinase in nymphs of T. infestans is accompanied by an increase in the amount of enzyme protein.
Moises Agosin, Jovita Ilivicky, S. Litvak   +2 more
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Immobilization of microbial cells containing NAD‐kinase

Biotechnology and Bioengineering, 1979
AbstractMicrobial cells having NAD‐kinase activity, Brevibacterium ammoniagenes, were immobilized by the radiation‐copolymerization method under low temperature with the activity recovery of more than 80%. Compared to the native microbial cells the immobilized cells were more stable against heat and pH change.
Toru Hayashi, Koji Kawashima, Yoshikazu Tanaka   +2 more
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Calmodulin-dependent NAD kinase of human neutrophils

Archives of Biochemistry and Biophysics, 1985
NAD kinase from human neutrophils has been partially purified by sequential application of Red Agarose, ion-exchange, and gel-filtration chromatography. The enzyme has a broad pH optimum, 7.0-9.5, is strictly dependent upon the presence of Mg2+, and in the absence of calcium exhibits Km values of 0.6 and 0.9 mM for NAD and ATP, respectively. NAD kinase
Mary B. Williams, Harold P. Jones
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