Results 91 to 100 of about 2,867 (123)

NAD(P)+ nucleosidase

open access: yes, 1991
Dietmar Schomburg, Margit Salzmann
openaire   +2 more sources

Evidence for NAD Nucleosidase in Rabbit-Liver Lysosomes

Canadian Journal of Biochemistry, 1975
A method is described for the isolation of secondary lysosomes from homogenates of rabbit liver. The uptake of Triton WR-1339 by rabbit-liver lysosomes when administered by intraperitoneal injection was used to decrease the density of secondary lysosomes. Lysosomal fractions prepared by this method contain an NAD nucleosidase (NAD glycohydrolase, EC 3.
A, Mellors, A K, Lun, O N, Peled
openaire   +2 more sources

Purification and properties of NAD nucleosidase from Fusarium nivale

Biochimica et Biophysica Acta (BBA) - Enzymology, 1973
Abstract 1. 1.|A highly active NAD nucleosidase (NAD glycohydrolase, EC 3.2.2.5) is synthesized by the snow mold Fusarium nivale. The activity appears in cell-bound or soluble form depending on the composition of the growth medium and the cultural conditions; formation of the enzyme seems related to the process of sporulation. 2.
D, Stathakos, I, Isaakidou, H, Thomou
openaire   +2 more sources

A quantitative assay for the cytoplasmic androgen receptor using [3H]dihydrotestosterone in the presence of NAD+-nucleosidase

Acta Endocrinologica, 1983
Abstract. In prostatic cytosol DHT1 is metabolized to 5α-androstane-3α (or β), 17α-diols with a half life of 2 h even at 4°C. Thus, [3H]DHT appears to be a poor marker for a quantitative assessment of androgen receptors (AR). Methyltrienolone (R1881) seems to be advantageous as it is not metabolized.
H, Moeller   +3 more
openaire   +2 more sources

Purification and some properties of NAD-degrading purine nucleosidase from Aspergillus niger

Canadian Journal of Biochemistry, 1978
An enzyme which degrades NAD at the adenine–ribose linkage has been purified from the mycelial extract of Aspergillus niger. NADP, deamido-NAD, and purine nucleosides and nucleotides were also susceptible to the hydrolytic cleavage. Pyrimidine- and nicotinamide–ribose linkages were not attacked.
M, Kuwhara, T, Fujii
openaire   +2 more sources

Inhibition of nuclear NAD nucleosidase and poly ADP-ribose polymerase activity from rat liver by nicotinamide and 5′-methyl nicotinamide

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1971
Abstract The effectiveness of nicotinamide and 5′-methyl nicotinamide as inhibitors of nuclear NAD nucleosidase and poly ADP-ribose polymerase from rat liver has been investigated. Nicotinamide inhibited the NAD nucleosidase and the poly ADP-ribose polymerase with Ki's of 5 · 10−4 M and 2 · 10−5 M, respectively, 5′-methyl nicotinamide with Ki's of 3 ...
J B, Clark, G M, Ferris, S, Pinder
openaire   +2 more sources

Structural and biochemical basis of NAD+ nucleosidase activity of TIR domain-containing proteins

2021
NAD+ (nicotinamide adenine dinucleotide) was first identified as a cofactor in many redox reactions. Subsequently, it has been found to synchronize many cellular functions through the regulation of NAD+ consuming enzymes like CD38, sirtuins, and PARPs (poly ADP-ribose polymerases).
openaire   +2 more sources

Streptococcal extracellular NAD+ nucleosidase. Characterization of changes occurring during purification

Folia Microbiologica, 1980
Purification of streptococcal extracellular NAD+ nucleosidase is associated with changes of kinetic properties. A high-molecular weight component is required for a full activity of the enzyme. The component is not produced by bacteria and is present in the Todd-Hewitt cultivation medium, the beef-heart extract serving primarily as its source.
openaire   +2 more sources

Safety assessment of purine nucleosidase from Aspergillus luchuensis

Toxicology Research and Application, 2021
Trung D Võ, Seth Floyd
exaly  

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