Results 91 to 100 of about 299,285 (291)
NAD precursors cycle between host tissues and the gut microbiome
bioRxiv, 2021 Nicotinamide adenine dinucleotide (NAD) is an essential redox cofactor in both mammals and microbes. Here we use isotope tracing to investigate the precursors supporting NAD synthesis in the gut microbiome.
K. Chellappa +19 more
semanticscholar +1 more source
Proceedings, 2019 Large river floods threaten intensively used urban areas across the world. Projections of IPCC expect such risks to increase in the future. To deal with flood risk along rivers water can be retained upstream at places where less damage is caused and more
Jan Brabec +2 more
doaj +1 more source
5D Rotating Black Holes and the nAdS$_2$/nCFT$_1$ Correspondence [PDF]
, 2018 We study rotating black holes in five dimensions using the nAdS$_2$/nCFT$_1$ correspondence. A consistent truncation of pure Einstein gravity (with a cosmological constant) in five dimensions to two dimensions gives a generalization of the Jackiw-Teitelboim theory that has two scalar fields: a dilaton and a squashing parameter that breaks spherical ...
arxiv +1 more source
Gravitational Anomalies in nAdS$_2$/nCFT$_1$ [PDF]
, 2019 We revisit the holographic description of the near horizon geometry of the BTZ black hole in AdS$_3$ gravity, with a gravitational Chern-Simons term included. After a dimensional reduction of the three dimensional theory, we use the framework of nAdS$_2$/nCFT$_1$ to describe the near horizon physics.
arxiv +1 more source
MCART1/SLC25A51 is required for mitochondrial NAD transport
Science Advances, 2020 We demystify how mitochondria obtain NAD, revealing that MCART1/SCL25A51 is required for NAD transport into mitochondria. The nicotinamide adenine dinucleotide (NAD+/NADH) pair is a cofactor in redox reactions and is particularly critical in mitochondria
Nora Kory +11 more
semanticscholar +1 more source
Regulation of NAD Biosynthesis in Salmonella typhimurium: Expression of nad--lac Gene Fusions and Identification of a nad Regulatory Locus [PDF]
Microbiology, 1985 Regulation of NAD biosynthesis was examined through the construction of nad-lac fusions in Salmonella typhimurium. The nadA (17 unit map position) and nadB (55 units) genetic loci involved with quinolinic acid biosynthesis were both found to be regulated by the product of a nadR locus (99 units) in a repression/derepression manner while nadC (3 units ...
Elizabeth A. Holley +2 more
openaire +2 more sources
Deciphering NAD-Dependent Deacetylases [PDF]
Cell, 2001 Structural comparisons between other Sir2p family members, especially of the zinc binding and helical domains, should reveal further clues to the sources of substrate specificity. This first structure of Sir2-Af1 represents a road map to guide construction of hybrid proteins aimed at deciphering the function of different family members.
Robert N. Dutnall, Lorraine Pillus
openaire +3 more sources
LandIn ore regions impacted by mining and metal smelting emissions, distinguishing between geogenic anomalies and anthropogenic contamination poses a significant challenge. In a study from two areas with different mining histories in the Ore Mountains, Czech
Michal Hošek +4 more
doaj +1 more source
Plants, 2020 Miscanthus x giganteus (Mxg) is a promising second-generation biofuel crop with high production of energetic biomass. Our aim was to determine the level of plant stress of Mxg grown in poor quality soils using non-invasive physiological parameters and to
Hana Malinská +5 more
doaj +1 more source
Answering two open problems on Banks theorem for non-autonomous dynamical systems [PDF]
arXiv, 2019 This paper shows that (1) there exists a topologically transitive NADS having two disjoint invariant periodic orbits with dense periodic points, which is finitely generated but not periodic; (2) there exists a topologically transitive non-finitely generated NADS having two disjoint invariant periodic orbits with dense periodic point, which is not ...
arxiv