Results 231 to 240 of about 268,882 (295)

Inflorescence Photosynthesis Determines Resource Allocation, Seed Production and Senescence in an Agricultural Weed

Plant, Cell &Environment, EarlyView.
ABSTRACT Agricultural weeds typically combine high reproductive output with fast vegetative growth. Here we analyzed the processes that overcome a potential trade‐off between vegetative growth and reproduction in the weed Avena fatua. We determined photosynthetic function of inflorescences and analyzed the transcriptomes of individual inflorescence ...
Soualihou Soualiou, Lucía Guerrero Cornejo, Israel Ikoyi, Rossana Henriques, Astrid Wingler   +4 more
wiley   +1 more source

Metabolic reprogramming of the immune response in periodontitis

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon, Melissa Grant, Iain Chapple, Joao Paulo Steffens   +3 more
wiley   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

Fluvastatin Plus Dipyridamole Suppresses Canine Hemangiosarcoma Growth in Patient‐Derived Xenograft Models Through Lactate Dehydrogenase‐Associated Cholesterol/Lipid Metabolism

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Tumour cells commonly exhibit aerobic glycolysis and produce lactate despite oxygen availability. Lactate dehydrogenase (LDH) catalyses pyruvate‐lactate interconversion and regulates intracellular lactate levels. Endothelial cells also depend on glycolysis for ATP production, which prompted us to investigate LDH in canine hemangiosarcoma (HSA),
Tamami Suzuki, Suzune Tanaka, Keika Kishimoto, Takuma Goto, Jumpei Yamazaki, Takashi Kimura, Keisuke Aoshima   +6 more
wiley   +1 more source

Mitochondrial alterations as potential early events in neuromuscular junction remodelling with muscle disuse

Experimental Physiology, EarlyView.
Abstract Physical inactivity impairs neuromuscular health, promoting skeletal muscle atrophy, mitochondrial changes, and neuromuscular junction (NMJ) instability. However, the interplay between mitochondria and NMJ alterations in the context of muscle disuse remains underexplored.
Evgeniia Motanova, Evgenii Lysenko, Fabio Sarto, Mladen Gasparini, Boštjan Šimunic, Rado Pišot, Marco V. Narici   +6 more
wiley   +1 more source

Photobiomodulation as a contemporary antioxidant intervention in myocardial infarction

Experimental Physiology, EarlyView.
Abstract Myocardial infarction (MI) triggers a complex cascade of structural and functional alterations that frequently culminate in adverse cardiac remodelling and heart failure. Central to this process is the excessive production of reactive oxygen species (ROS), which disrupt mitochondrial function, impair calcium handling, and activate pro ...
Gabriel Matheus Da Silva Batista, Ighor Luiz Azevedo Teixeira, Ednei Luiz Antonio, Andrey Jorge Serra   +3 more
wiley   +1 more source

The assembly of tetrameric human L-lactate dehydrogenase is regulated by ionic strength, β-NADH binding, cyclic peptides, and long-chain dicarboxylates. [PDF]

Protein Sci
Stefan A, Gentilucci L, Barbiroli AG, Rossi V, Liao H, Di Stefano G, He T, Hochkoeppler A.   +7 more
europepmc   +1 more source

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Reduction of Oxygen by NADH/NADH Dehydrogenase in the Presence of Adriamycin

Free Radical Research Communications, 1986
Cardiac mitochondrial NADH dehydrogenase (Cytochrome c reductase, EC1.6.99.3) catalyses the reduction of ferricytochrome c to ferrocytochrome c by NADH. In the presence of the anthracycline anti-tumour drug, adriamycin, electron transfer from NADH is subverted to dioxygen.
Paul J Thornalley, W H Bannister, J V Bannister   +2 more
exaly   +3 more sources

Interaction of Rhodanese With Mitochondrial NADH Dehydrogenase

BBA - Proteins and Proteomics, 1983
NADH dehydrogenase is an iron-sulfur flavoprotein which is isolated and purified from Complex I (mitochondrial NADH: ubiquinone oxidoreductase) by resolution with NaClO4. The activity of the enzyme (followed as NADH: 2-methylnaphthoquinone oxidoreductase) increases linearly with protein concentration (in the range between 0.2 and 1.0 mg/ml) and ...
Y M Galante, Silvia Maria Carla Pagani, Y M Galante   +2 more
exaly   +3 more sources