Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, Volume 12, Issue 30, August 14, 2025.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
N matters: Insights into nitrogen assimilation from the ectomycorrhizal fungus Laccaria bicolor. [PDF]
Plant PhysiolKhan M.
europepmc +1 more source
An NADP-linked 15-hydroxyprostaglandin dehydrogenase specific for prostaglandin D2 from swine brain.
, 1982 Hidekado Tokumoto +4 more
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The role of glutamate in modulating the synthesis and degradation of NADP-glutamate dehydrogenase from Saccharomyces cerevisiae [PDF]
, 1985 Elena Bogónez +2 more
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Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering
ChemCatChem, Volume 17, Issue 16, August 18, 2025.A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer +7 more
wiley +1 more source
Confocal Laser Scanning Microscopy of Light-Independent ROS in <i>Arabidopsis thaliana</i> (L.) Heynh. TROL-FNR Mutants. [PDF]
Int J Mol SciDumančić E, Vojta L, Fulgosi H.
europepmc +1 more source
Novel nitrogen sources for growth of Bacillus fastidiosus and their effect on the activity of NADP-dependent glutamate dehydrogenase [PDF]
, 1993 M Muruke
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Genomic Landscape of High‐Altitude Adaptation in East African Mountain Honey Bees (Apis mellifera)
Ecology and Evolution, Volume 15, Issue 8, August 2025.Highland and lowland honey bees in East Africa exhibit distinct phenotypes despite low overall genetic differentiation. To investigate this further, we sampled honey bees from a mountain system in Uganda (red circle) and compared them with samples from Kenya.
Marco Mazzoni +8 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2015 Nick R. Love +8 more
semanticscholar +1 more source