Results 211 to 220 of about 143,400 (355)

Co‐existence of two regulatory NADP‐glyceraldehyde 3‐P dehydrogenase complexes in higher plant chloroplasts [PDF]

open access: bronze, 2002
Renate Scheibe   +4 more
openalex   +1 more source

Physiologically‐Based Pharmacokinetic Modeling of the PARP Inhibitor Niraparib

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT A physiologically‐based pharmacokinetic (PBPK) model of niraparib and its primary metabolite using a relevant virtual cancer population is reported here. A series of in vitro experiments using liver S9, microsomes, and hepatocytes with various inhibitors and recombinant supersomes demonstrated that niraparib is specifically metabolized by ...
Gareth J. Lewis   +3 more
wiley   +1 more source

Functionalizing Nucleic Acids: Synthesis and Purification Strategies for Bioconjugates as Biomaterials

open access: yesSmall, Volume 22, Issue 5, 22 January 2026.
Nucleic acid‐ligand conjugates combine the distinct properties of macromolecular ligands with the versatility of DNA/RNA nanotechnology. In biomaterial and nanomedicine applications, highly purified products are paramount, requiring reliable synthesis and purification methods.
Nico Alleva   +4 more
wiley   +1 more source

Climate and Anthropogenic Perturbations Impact Stream Geochemistry

open access: yesEarth's Future, Volume 14, Issue 1, January 2026.
Abstract Climate and anthropogenic perturbations, including warming temperatures, shifting precipitation patterns, and changes in contamination, can alter geochemical reactions that shape stream chemistry. To date, our understanding of how climate and humans are altering water‐rock interactions and geogenic stream chemistry is limited, partly because ...
S. Warix   +2 more
wiley   +1 more source

Loss of Nocturnin increases neuronal viability in oxidative stress conditions. [PDF]

open access: yesFront Neurosci
Ojo AE   +3 more
europepmc   +1 more source

Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia

open access: yesIET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study provides reference for fatty acid metabolism related potential candidate genes for sarcopenia and initially creates an effective machine learning models for further investigating the direction of the mechanism level. ABSTRACT Sarcopenia is an ageing‐related disease characterised primarily by skeletal muscle functional decline.
Ruopeng Yang, Shan Gu, Yang Li, Ping Xia
wiley   +1 more source

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