Results 231 to 240 of about 338,563 (360)

Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells

open access: yesCell Biology International, EarlyView.
ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros   +3 more
wiley   +1 more source

Thermostable enzyme isoforms, continuously producing monocomponent superoxide radicals, from human postoperative serous fluids: isolation and properties. [PDF]

open access: yesBMC Cancer
Simonyan RM   +11 more
europepmc   +1 more source

Electrochemical Breath Sensors in Medical Diagnostics: Emerging Trends and Future Directions

open access: yesChemElectroChem, EarlyView.
Electrochemical breath sensors (EBSs) are emerging as powerful tools for noninvasive health diagnostics. This perspective highlights recent advances in EBS technologies, explores their potential in mental health monitoring via gut‐derived volatile organic compounds, and outlines future directions for achieving sensitive, selective, and clinically ...
Natalie E. Strom   +2 more
wiley   +1 more source

<i>In vivo</i> functional screening on innate immunity of lactic acid bacteria in <i>Galleria mellonella</i> preclinical model: comparative analysis of <i>Lactiplantibacillus plantarum</i> and <i>Lentilactobacillus kefiri</i>. [PDF]

open access: yesFront Cell Infect Microbiol
Guarnieri A   +10 more
europepmc   +1 more source

Dietary Berberine Reduced Oxido‐Inflammatory Stress in Rats' Livers and Kidneys, Supplemented from Prepuberty to Adulthood

open access: yesChemFoodChem, EarlyView.
Berberine (BER) demonstrates significant protective effects on the hepatorenal system in rats, mediated through various cellular and molecular mechanisms spanning from the prepubertal stage through adulthood. These mechanisms encompass antioxidant, anti‐inflammatory, and anti‐apoptotic activities, in addition to modulation of essential signalling ...
Solomon Owumi   +8 more
wiley   +1 more source

From Binding to Catalysis: Emergence of a Rudimentary Enzyme Conferring Intrinsic Antibiotic Resistance. [PDF]

open access: yesMol Biol Evol
Lemay-St-Denis C   +8 more
europepmc   +1 more source

Substitution of CH3 by CH2F in 2‐Methylerythritol Cyclodiphosphate Triggers Potent Inhibition of IspG with Concomitant Fluoride Ion Expulsion

open access: yesChemistry – A European Journal, EarlyView.
The fluoromethyl analogue of MEcPP was identified as a very potent inhibitor of the oxygen‐sensitive [4Fe‐4S] metalloenzyme IspG. In the course of the IspG‐catalyzed transformation, this novel compound undergoes fluoride elimination, offering additional evidence for the involvement of a carbanionic intermediate in the mechanism of this enzyme ...
Clea Witjaksono   +7 more
wiley   +1 more source

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