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Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

open access: green, 2014
Caroline A. Lewis   +9 more
openalex   +1 more source

NADPH oxidase

The International Journal of Biochemistry & Cell Biology, 1996
Superoxide is instrumental in the killing of microorganisms by phagocytic cells. It is generated by the NADPH oxidase system, a membrane-bound electron transport complex which pumps electrons from NADPH in the cytoplasm across the wall of the phagocytic vacuole to molecular oxygen.
K P, Shatwell, A W, Segal
openaire   +2 more sources

Mammalian NADPH Oxidases

2019
Reactive oxygen species (ROS) are highly reactive oxygen derivatives. Initially, they were considered as metabolic by-products (of mitochondria in particular), which consistently lead to aging and disease. Over the last decades, however, it became increasingly apparent that virtually all eukaryotic cells possess specifically ROS-producing enzymes ...
Hélène, Buvelot   +2 more
openaire   +2 more sources

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