The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. [PDF]
People heterozygous for an activating mutation in protein kinase G1 (PRKG1, p.Arg177Gln) develop thoracic aortic aneurysms and dissections (TAAD) as young adults.
Boss, Gerry R+15 more
core +1 more source
Interactions of rare earth elements with living organisms and emerging biotechnical applications
Rare earth elements (REEs) are critical resources required to achieve net‐zero carbon emission targets and energy security. However, rising demand for REEs coupled with significant extraction and processing challenges and geopolitical risks restricts access to REE resources.
Samantha A. McGaughey+6 more
wiley +1 more source
X-linked chronic granulomatous disease: correction of NADPH oxidase defect by retrovirus-mediated expression of gp91-phox [PDF]
Stephen Porter+4 more
openalex +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho+10 more
wiley +1 more source
Current status of NADPH oxidase research in cardiovascular pharmacology
Bruno K Rodiño-Janeiro,1,2 Beatriz Paradela-Dobarro,1 María Isabel Castiñeiras-Landeira,1 Sergio Raposeiras-Roubín,1,3 José R González-Juanatey,1,3,4 Ezequiel Álvarez1,4 1Health Research Institute of ...
Rodiño-Janeiro BK+5 more
doaj
Autosomal recessive chronic granulomatous disease with absence of the 67-kD cytosolic NADPH oxidase component: identification of mutation and detection of carriers [PDF]
Martin de Boer+7 more
openalex +1 more source
NADPH oxidase AtrbohD and AtrbohF genes function in ROS‐dependent ABA signaling in Arabidopsis
J. Kwak+9 more
semanticscholar +1 more source
Hydrochlorothiazide plus combined exercise training provides superior benefits compared to medication alone in female spontaneously hypertensive rats subjected to ovarian hormone deprivation. This combined approach significantly reduced blood pressure variability, improved inflammatory and redox profiles, and provided functional and morphological ...
Pietra Petrica Neves+6 more
wiley +1 more source