Results 241 to 250 of about 442,921 (391)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

Correction: Endothelial AIP1 regulates vascular remodeling by suppressing NADPH Oxidase-2. [PDF]

Front Physiol
Zhang J, Chen C, Li L, Zhou HJ, Li F, Zhang H, Yu L, Chen Y, Min W.   +8 more
europepmc   +1 more source

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

, 1993
Mark T. Quinn, Timothy A. Evans, Linda R. Loetterle, Algirdas J. Jesaitis, Gary Bokoch   +4 more
openalex   +1 more source

Insights Into Macrophage Ferroptosis: Implications for Atherosclerosis

Cell Proliferation, EarlyView.
Macrophage ferroptosis drives atherosclerosis by enhancing oxidative stress and inflammation, accelerating plaque progression and instability. Targeting macrophage ferroptosis presents a promising therapeutic strategy for atherosclerosis treatment.
Xiehui Chen, Xiangbo Liu, Changchun Zeng
wiley   +1 more source

Circadian Control of Pulmonary Endothelial Signaling Occurs via the NADPH Oxidase 2-NLRP3 Pathway. [PDF]

J Biol Rhythms
Sengupta S, Lee Y, Tao JQ, Akolia I, Louneva N, Forrest K, Paul O, Brooks TG, Grant GR, Sehgal A, Chatterjee S.   +10 more
europepmc   +1 more source

NADPH Oxidase-induced oxidative stress enhances VEGF synthesis under hyperglycemic condition in ARPE-19 cells.

, 2016
Rashidul Haque, P. Michael Iuvone, Elizabeth H. Hur, Kimberly Sc Choi, Daniel Park, Annie Farrell, Li He, Samantha Gokhale, Bhavna Kumar   +8 more
openalex   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease. [PDF]

Adv Sci (Weinh)
Lee J, Sim S, Jin Y, Park H, Byeon EY, Kim SJ, Yun S, Lee HE, Jeong DU, Suh JM, Lee IH, Lee HY, Choi Y, Bae YS.   +13 more
europepmc   +1 more source

Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy.

Journal of the American Society of Nephrology, 2014
J. Jha, S. Gray, D. Barit, J. Okabe, A. El-Osta, T. Namikoshi, V. Thallas‐Bonke, K. Wingler, C. Szyndralewiez, F. Heitz, R. Touyz, M. Cooper, H. Schmidt, K. Jandeleit-Dahm   +13 more
semanticscholar   +1 more source

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase [PDF]

, 2007
Sang Won Suh, Elizabeth T. Gum, Aaron M. Hamby, Pak H. Chan, Raymond A. Swanson   +4 more
openalex   +1 more source