Results 261 to 270 of about 180,191 (302)

Receptor Activation of NADPH Oxidases

Antioxidants & Redox Signaling, 2010
Reactive oxygen species (ROS) have been implicated in many intra- and intercellular processes. High levels of ROS are generated as part of the innate immunity in the respiratory burst of phagocytic cells. Low levels of ROS, however, are generated in a highly controlled manner by various cell types to act as second messengers in redox-sensitive pathways.
Andreas, Petry, Michael, Weitnauer, Agnes, Görlach   +2 more
openaire   +2 more sources

NADPH oxidases and cardiac remodelling

Heart Failure Reviews, 2010
A heart under chronic stress undergoes cardiac remodelling, a process that comprises structural and functional changes including cardiomyocyte hypertrophy, interstitial fibrosis, contractile dysfunction, cell death and ventricular dilatation. Reactive oxygen species (ROS)-dependent modulation of intracellular signalling is implicated in the development
Nabeebaccus, Adam, Zhang, Min, Shah, Ajay M.   +2 more
openaire   +3 more sources

NADPH Oxidase: An Update

Blood, 1999
T HE NADPH OXIDASES are a group of plasma membrane–associated enzymes found in a variety of cells of mesodermal origin. The most thoroughly studied of these is the leukocyte NADPH oxidase, which is found in professional phagocytes and B lymphocytes.
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NADPH Oxidases in the Kidney

Antioxidants & Redox Signaling, 2006
NADPH oxidases have a distinct cellular localization in the kidney. Reactive oxygen species (ROS) are produced in the kidney by fibroblasts, endothelial cells (EC), vascular smooth muscle cells (VSMC), mesangial cells (MCs), tubular cells, and podocyte cells.
Pritmohinder S, Gill, Christopher S, Wilcox   +1 more
openaire   +2 more sources

NADPH oxidase and heart failure

Current Opinion in Pharmacology, 2006
Reactive oxygen species play important roles in the pathophysiology of chronic heart failure secondary to chronic left ventricular hypertrophy or myocardial infarction. Reactive oxygen species influence several components of the phenotype of the failing heart, including contractile function, interstitial fibrosis, endothelial dysfunction and myocyte ...
Murdoch, Colin E., Grieve, David J., Cave, Alison C., Looi, Yee Hoo, Shah, Ajay M.   +4 more
openaire   +3 more sources

Role of Nadph Oxidase in Atherosclerosis

Future Cardiology, 2008
Reactive oxidant species (ROS) seem to play a key role in the atherosclerotic process via a series of molecular changes that lead to macrophage infiltration in the endothelium and eventually to plaque formation. ROS are also implicated in arterial dysfunction via inactivation of nitric oxide, a potent vasodilator and antiaggregating molecule produced ...
VIOLI, Francesco, BASILI, Stefania, Carmen Nigro, PIGNATELLI, Pasquale   +3 more
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Localizing NADPH Oxidase–Derived ROS

Science's STKE, 2006
Reactive oxygen species (ROS) function as signaling molecules to mediate various biological responses, including cell migration, growth, and gene expression. ROS are diffusible and short-lived molecules. Thus, localizing the ROS signal at the specific subcellular compartment is essential for activating redox signaling events after receptor activation ...
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NADPH oxidase(s)

Journal of clinical pathology, 2002
Reactive oxygen species play an important role in a variety of (patho)physiological vascular processes. Recent publications have produced evidence of a role for putative non-phagocyte NADP oxidase(s) in the vascular production of reactive oxygen species.
Van Heerebeek, L, Meischl, C, Stooker, W, Meijer, C J L M, Niessen, H W M, Roos, D   +5 more
openaire   +1 more source

NADPH AND NADPH OXIDASE

2006
A.B. Fisher, Q. Zhang
openaire   +1 more source

Plant NADPH Oxidases

2023
Gad Miller, Ron Mittler
openaire   +1 more source