Results 201 to 210 of about 296,542 (336)

NADPH oxidases in traumatic brain injury – Promising therapeutic targets?

open access: yesRedox Biology, 2018
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Despite intense investigation, no neuroprotective agents for TBI have yet translated to the clinic.
Merry W. Ma   +4 more
doaj  

Low‐Intensity Pulsed Ultrasound Treatment Selectively Stimulates Senescent Cells to Promote SASP Factors for Immune Cell Recruitment

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
The regulatory effects of low‐intensity pulsed ultrasound (LIPUS) stimulation in senescent cells are presented. LIPUS perturbs the membrane in senescent cells and induces intracellular reactive oxygen species via NOX4 expression. Consequently, secretion of senescence‐associated secretory phenotype, followed by migration of monocytes/macrophages and ...
HyeRan Gwak   +7 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

NADPH Oxidases in Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction. [PDF]

open access: yesAntioxidants (Basel), 2022
Teuber JP   +4 more
europepmc   +1 more source

Unraveling Alveolar Fibroblast and Activated Myofibroblast Heterogeneity and Differentiation Trajectories During Lung Fibrosis Development and Resolution in Young and Old Mice

open access: yesAging Cell, Volume 24, Issue 5, May 2025.
Model of LIF‐to‐aMYF reversible switch during fibrosis formation and resolution in old mice. The main contributors during fibrosis formation to Cthrc1+ aMYF are Acta2+ LIFhigh alveolar fibroblasts. During fibrosis resolution, Cthrc1+ aMYF differentiate back to the LIFhigh (please write "high" in superscript) alveolar fibroblasts cluster.
Arun Lingampally   +18 more
wiley   +1 more source

Downregulation of NAD Kinase Expression in β‐Cells Contributes to the Aging‐Associated Decline in Glucose‐Stimulated Insulin Secretion

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Adequate NADK/NADK2 level is essential to the proper functioning of redox and folate cycles and the purine biosynthesis pathway, and as well as maintenance of GSIS response. During aging, diminished NADK/NADK2 expression alters the metabolic status quo, increasing AICAR production. The latter activates AMPK and suppresses GSIS.
Guan‐Jie Li   +6 more
wiley   +1 more source

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

open access: green, 1994
Hidetoshi Sumimoto   +8 more
openalex   +1 more source

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