Results 181 to 190 of about 42,623 (284)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Roles of NADPH oxidases in regulating redox homeostasis and pathogenesis of the poplar canker fungus Cytospora chrysosperma. [PDF]

Stress Biol
Li Q, Guo R, Li A, Wang Y.
europepmc   +1 more source

Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica. [PDF]

Korean J Parasitol, 2022
Lee YA, Sim S, Kim KA, Shin MH.
europepmc   +1 more source

Asynchrony Related to Mechanical Ventilation Exacerbates Diaphragm Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims In dystrophic mice (mdx, a genetic homolog of Duchenne muscular dystrophy: DMD), previous studies showed that mechanical ventilation (MV) induces ventilator‐induced diaphragmatic dysfunction (VIDD). However, susceptibility to mechanical stress caused by asynchrony remains unknown.
Mohamad Yehya, Haikel Dridi, Eric Estève, Johan Moreau, Steven Reiken, Andrew R. Marks, Alain Lacampagne, Stefan Matecki   +7 more
wiley   +1 more source

Regulation of cardiovascular diseases by histone deacetylases and NADPH oxidases. [PDF]

Redox Biol
Yan H, Yin Y, Zhou Y, Li Z, Li Y, Ren L, Wen J, Wang W.   +7 more
europepmc   +1 more source

NADPH Oxidases Play a Role in Pathogenicity via the Regulation of F-Actin Organization in Colletotrichum gloeosporioides. [PDF]

Front Cell Infect Microbiol, 2022
Liu N, Wang W, He C, Luo H, An B, Wang Q.   +5 more
europepmc   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Portal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang, Zhenyu Liu, Jun Lin, Weijing Zhang, Xianzhi Liu, Tong Zhang   +5 more
wiley   +1 more source

Multifaceted roles of NADPH oxidases in the growth and pathogenicity of <i>Beauveria bassiana</i>. [PDF]

Virulence
Zhu S, Wang J, Liu Y, Jin D, Luo X, Wan M, Fan Y.   +6 more
europepmc   +1 more source

Translating the oxidative stress hypothesis into the clinic: NOX versus NOS [PDF]

, 2009
Melanie E. Armitage, Kirstin Wingler, Harald H. H. W. Schmidt, Mylinh La, E Schulz, GM Rubanyi, H Mollnau, JP Stasch, OV Evgenov, S Meurer, PI Nedvetsky, CA Papaharalambus, K Bedard, S Moncada, R Schulz, RH Boger, SM Morris Jr, ZS Katusic, MJ Eliasson, JP Cobb, AC Tinker, P Brouckaert, JR Stone, A Daiber, FN Ko, JP Stasch, J Mittendorf, JP Stasch, F Akker van Den, H Lapp, JD Lambeth, DD Heistad, N Opitz, BM Babior, KK Griendling, A Cave, H Sumimoto, MS Bitar, DI Brown, RP Brandes, S Spiekermann, TJ Guzik, TJ Guzik, TJ Guzik, Y Dotan, S Heumuller, H Freyhaus ten, C Stielow, GM Jacobson, HC Williams, JD Lambeth, S Selemidis, RM Palmer   +52 more
core   +1 more source

NADPH Oxidase 4 [PDF]

, 2020
openaire   +1 more source