Results 161 to 170 of about 42,623 (284)

NADPH Oxidases in Diastolic Dysfunction and Heart Failure with Preserved Ejection Fraction. [PDF]

Antioxidants (Basel), 2022
Teuber JP, Essandoh K, Hummel SL, Madamanchi NR, Brody MJ.   +4 more
europepmc   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen, Yong‐Hong Yu, Yan‐Hua Du, Lin Xu, Xiang‐Ping Meng   +4 more
wiley   +1 more source

Dynamic regulation of receptor-modulated endothelial NADPH oxidases. [PDF]

Proc Natl Acad Sci U S A
Waldeck-Weiermair M, Das AA, Covington TA, Meitzler JL, Doroshow JH, Duan J, Fong YW, Kaynert J, Yadav S, Dutta T, Spyropoulos F, Pandey AK, Michel T.   +12 more
europepmc   +1 more source

Enzymology of Ca²⁺-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases. [PDF]

Cells, 2023
Guse AH.
europepmc   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Nox, Nox, Are You There? The Role of NADPH Oxidases in the Peripheral Nervous System. [PDF]

Antioxid Redox Signal, 2022
Eid SA, Savelieff MG, Eid AA, Feldman EL.   +3 more
europepmc   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Expression, localization and regulation of NADPH oxidases in pancreatic beta cells. [PDF]

Redox Rep
de Almeida DC, Vilas-Boas EA, Coelho Ferreira PH, Ferreira SM, Carpinelli AR, Ortis F.   +5 more
europepmc   +1 more source

Effects of aerobic exercise on cardiac function and gene expression of NADPH oxidases in diaphragm muscle of rats with aortic stenosis-induced heart failure. [PDF]

Front Physiol, 2023
Janini Gomes M, Sabela AK, Ferreira ITP, de Souza SLB, Mota GAF, da Silva VL, de Campos DHS, Lima ARR, Carvalho MR, Bazan SGZ, Corrêa CR, Cicogna AC, Okoshi MP, Pacagnelli FL.   +13 more
europepmc   +1 more source