Results 201 to 210 of about 25,108 (267)

Contrasting effects of NADPH oxidases on the fungal hyphae growth and immune responses in Pleurotus ostreatus. [PDF]

Front Microbiol
Li H, Zhu J, Li Z, Xu P, Ma L, Zou Y, Qu S, Wu X.   +7 more
europepmc   +1 more source

Crosstalk Between SMPDL3b and NADPH Oxidases Mediates Radiation-Induced Damage of Renal Podocytes. [PDF]

Front Med (Lausanne), 2021
Azzam P, Francis M, Youssef T, Mroueh M, Daher AA, Eid AA, Fornoni A, Marples B, Zeidan YH.   +8 more
europepmc   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

British Journal of Haematology, EarlyView.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed, Rattanaporn Praneetponkang, Potchaman Sittipaisankul, Chayada Thiengtavor, Suwathida Chumpuchanaphai, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Duncan R. Smith, Saovaros Svasti, Pornthip Chaichompoo   +11 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

NADPH-oxidases as potential pharmacological targets for thrombosis and depression comorbidity. [PDF]

Redox Biol
Amadio P, Sandrini L, Zarà M, Barbieri SS, Ieraci A.   +4 more
europepmc   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira, Edson Antunes, Fabiola Zakia Monica, Gilberto De Nucci   +3 more
wiley   +1 more source

Correction for Waldeck-Weiermair et al., Dynamic regulation of receptor-modulated endothelial NADPH oxidases. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

The NADPH oxidases DUOX1 and DUOX2 are sorted to the apical plasma membrane in epithelial cells via their respective maturation factors DUOXA1 and DUOXA2. [PDF]

Genes Cells
Kohda A, Kamakura S, Hayase J, Sumimoto H.   +3 more
europepmc   +1 more source