Results 31 to 40 of about 28,923 (304)
Brain Sciences, 2013 Oxidative stress caused by an excess of reactive oxygen species (ROS) is known to contribute to stroke injury, particularly during reperfusion, and antioxidants targeting this process have resulted in improved outcomes experimentally. Unfortunately these
Carli L. Roulston, Sarah K. McCann
doaj +1 more source
Coding Synthetic Chemistry Strategies for Furan Valorization into Bacterial Designer Cells**
ChemSusChem, Volume 16, Issue 2, January 20, 2023., 2023 Designer cells: A microbial factory is designed to directly convert furfuryl alcohols to synthetically valuable and enantioenriched delta‐lactones. Pairing Achmatowicz ring expansions and borrowing hydrogen redoxisomerizations, two otherwise non‐natural transformations, this study highlights the potential of introducing novel biocatalytic tools into ...
Yu‐Chang Liu +2 more
wiley +1 more source
Polymer coated cerium oxide nanoparticles as oxidoreductase-like catalysts [PDF]
ACS Appl. Mater. Interfaces 2020, 12, 37, 42056 - 42066, 2020 Cerium oxide nanoparticles have been shown to mimic oxidoreductase enzymes by catalyzing the decomposition of organic substrates and reactive oxygen species. This mimicry can be found in superoxide radicals and hydrogen peroxides, harmful molecules produced in oxidative stress asso-ciated diseases.
arxiv +1 more source
Effects of Angiotensin II on the Cerebral Circulation: Role of Oxidative Stress
Frontiers in Physiology, 2013 Oxidative stress has emerged as a key component of many diseases that affect the vasculature. Oxidative stress is characterized as a cellular environment where the generation of oxidant molecules overwhelms endogenous antioxidant defense mechanisms ...
Travice Michael De Silva, Frank eFaraci
doaj +1 more source
NADPH Oxidases Are Involved in Differentiation and Pathogenicity in Botrytis cinerea
Molecular Plant-Microbe Interactions, 2008 Nicotinamide adenine dinucleotide (NADPH) oxidases have been shown to be involved in various differentiation processes in fungi. We investigated the role of two NADPH oxidases in the necrotrophic phytopathogenic fungus, Botrytis cinerea. The genes bcnoxA
Nadja Segmüller +5 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría +1 more
wiley +1 more source
Kinetics of proton pumping in cytochrome c oxidase [PDF]
J. Chem. Phys. 130, 235105 (2009), 2008 We propose a simple model of cytochrome c oxidase, including four redox centers and four protonable sites, to study the time evolution of electrostatically coupled electron and proton transfers initiated by the injection of a single electron into the enzyme.
arxiv +1 more source
The thioredoxin system: Balancing redox responses in immune cells and tumors
European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023 The thioredoxin (TRX) system is a critical contributor to cellular redox homeostasis in all living cells. Here, we review the key roles of TRX for activation, proliferation, and responses in T cells, B cells, and myeloid cells. Further, we conceptualize how this knowledge may be therapeutically exploited for cancer treatment.
Jonathan Muri, Manfred Kopf
wiley +1 more source
Mathematical Model for Chemical Reactions in Electrolyte Applied to Cytochrome $c$ Oxidase: an Electro-osmotic Approach [PDF]
arXiv, 2022 A mathematical model for chemical reactions in electrolytes is developed using an Energy variational method consistent with classical thermodynamics. Electrostatics and chemical reactions are included in properly defined energetic and dissipative functionals.
arxiv
The NADPH Oxidase of Endothelial Cells [PDF]
IUBMB Life, 2000 AbstractThe best known NADPH oxidase is that of phagocytes‐ neutrophils and monocytes. In these cells, the enzyme manufactures large quantities of O2 ‐ and other reactive oxidants that are used for the purpose of killing invading microorganisms. Recent studies, however, have suggested that a number of other tissues contain NADPH oxidases.
openaire +3 more sources