Results 61 to 70 of about 7,446 (257)

Repurposing in vitro approaches for screening anti-parasitic drugs against the brain-eating amoeba Naegleria fowleri

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2021
Naegleria fowleri is both a pathogenic and a free-living microbial eukaryote, responsible for the development of primary amoebic meningoencephalitis (PAM) in humans.
Rubén Martín-Escolano   +5 more
doaj   +1 more source

Isolation and Environmental Detection of Balamuthia mandrillaris in Isfahan, Iran

open access: yesEnvironmental Microbiology Reports, Volume 17, Issue 5, October 2025.
This study investigates the presence of Balamuthia mandrillaris in environmental sources from Isfahan, Iran, and compares cultural and molecular detection methods. The findings highlight matrix‐dependent detection patterns and report an overall prevalence of 15.6%.
Sara Lesani   +2 more
wiley   +1 more source

Meningoencephalitis by Naegleria fowleri: epidemiological study in Anzoategui state, Venezuela Meningoencefalite por Naegleria fowleri: estudo epidemiológico no Estado de Anzoategui, Venezuela

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2006
A case of primary amoebic meningoencephalitis produced by Naegleria fowleri was diagnosed in the Independencia county of Anzoategui State, Venezuela. This case motivated the realization of the present epidemiological study with the aim of identifying ...
Julman R. Cermeño   +7 more
doaj   +1 more source

Isolation and Identification of Naegleria Species in Irrigation Channels for Recreational Use in Mexicali Valley, Mexico

open access: yesPathogens, 2020
Members of the genus Naegleria are free-living amoebae that are widely distributed in water and soil environments. Moreover, Naegleria fowleri is a pathogenic amoeba species that causes a fatal disease in the central nervous system known as primary ...
Patricia Bonilla-Lemus   +9 more
doaj   +1 more source

Conserved actin machinery drives microtubule-independent motility and phagocytosis in Naegleria

open access: yesJournal of Cell Biology, 2020
Naegleria diverged from the “yeast-to-human” lineage >1 billion years ago. Velle and Fritz-Laylin found that Naegleria, which lacks interphase microtubules, has a robust actin cytoskeletal repertoire and uses conserved, Arp2/3–derived actin networks to ...
Katrina B. Velle, L. Fritz-Laylin
semanticscholar   +1 more source

The genome of Naegleria lovaniensis, the basis for a comparative approach to unravel pathogenicity factors of the human pathogenic amoeba N. fowleri

open access: yesBMC Genomics, 2018
Background Members of the genus Naegleria are free-living eukaryotes with the capability to transform from the amoeboid form into resting cysts or moving flagellates in response to environmental conditions.
Nicole Liechti   +3 more
doaj   +1 more source

A Deeply Branching Lineage in Heterolobosea (Discoba) With Multiflagellated and Multigrooved Life Stages

open access: yesJournal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT Several distantly related, deep‐branching lineages within the eukaryotic tree of life share what is known as the “typical excavate” morphology. This cell architecture includes a suspension‐feeding ventral groove, supported by complex and specific structures of the cytoskeleton, and a vane‐bearing posterior flagellum.
Kristina I. Prokina   +7 more
wiley   +1 more source

Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review

open access: yesClinical and Experimental Pharmacology and Physiology, 2019
Naegleria fowleri, a thermophilic flagellate amoeba known as a “brain‐eating” amoeba, is the aetiological agent of a perilous and devastating waterborne disease known as primary amoebic meningoencephalitis (PAM), both in humans as well as in animals. PAM
Muhammad Jahangeer   +8 more
semanticscholar   +1 more source

Environmental abiotic and biotic factors affecting the distribution and abundance of Naegleria fowleri

open access: yesFEMS Microbiology Ecology, 2020
Naegleria fowleri is a free-living protozoan that resides in soil and freshwater. Human intranasal amoebae exposure through water or potentially dust particles can culminate in primary amoebic meningoencephalitis, which generally causes death. While many
Leigha M. Stahl, J. Olson
semanticscholar   +1 more source

Isolation and Molecular Identification of Acanthamoeba and Naegleria from Agricultural Water Canal in Qazvin, Iran

open access: yesIranian Journal of Parasitology, 2020
Background: Free-living amoeba (FLA) are widely distributed in different environmental sources. The most genera of the amoeba are Acanthamoeba, Naegleria and Vermamoeba.
Mandana KHORSANDI RAFSANJANI   +4 more
doaj   +1 more source

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