Pathogens, 2020 Members of the genus Naegleria are free-living amoebae that are widely distributed in water and soil environments. Moreover, Naegleria fowleri is a pathogenic amoeba species that causes a fatal disease in the central nervous system known as primary ...
Patricia Bonilla-Lemus +9 more
doaj +1 more source
Primary Amoebic (Naegleria fowleri) Meningoencephalitis Presenting as Status Epilepticus [PDF]
, 2011 Primary amebic meningoencephalitis (PAM) is a rare entity. Usual presenting features are fever, headache and seizures with meningeal signs and this disease carries high mortality rate.
Bharti, V +5 more
core +1 more source
Protozoan-induced regulation of cyclic lipopeptide biosynthesis Is an effective predation defense mechanism for Pseudomonas fluorescens [PDF]
, 2009 Environmental bacteria are exposed to a myriad of biotic interactions that influence their function and survival. The grazing activity of protozoan predators significantly impacts the dynamics, diversification, and evolution of bacterial communities in ...
Bruijn, I., de +3 more
core +3 more sources
Ultrastructure of Naegleria fowleri enflagellation [PDF]
Journal of Bacteriology, 1981 Amoebae of Naegleria fowleri nN68 became elongated flagellated cells 150 to 180 min after subculture to non-nutrient buffer. N. fowleri NF69 did not become elongated or flagellated under these conditions. Electron microscopic examination of N. fowleri confirmed that it is a typical eucaryotic protist with a distinct nuclear envelope and prominent ...
M, Patterson +3 more
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Frontiers in MicrobiologyNaegleria fowleri is the causative agent of primary amoebic meningoencephalitis, a rapid and acute infection of the central nervous system with a fatal outcome in >97% of cases.
L. Moreira +14 more
semanticscholar +1 more source
Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review
Clinical and Experimental Pharmacology and Physiology, 2019 Naegleria fowleri, a thermophilic flagellate amoeba known as a “brain‐eating” amoeba, is the aetiological agent of a perilous and devastating waterborne disease known as primary amoebic meningoencephalitis (PAM), both in humans as well as in animals. PAM
Muhammad Jahangeer +8 more
semanticscholar +1 more source
Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred
Protein Science, Volume 35, Issue 2, February 2026.Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong +2 more
wiley +1 more source
The in vitro and in vivo testing of chemotherapeutic agents against pathogenic free living amebae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, Palmerston North, New Zealand. [PDF]
, 1980 During the last ten years, there has been an increasing awareness of sporadic cases of Primary Amoebic Meningo-encephalitis (PAM) affecting primarily younger age groups and appearing in an acute fulminant form. The earliest positive case (Willaert, 1974)
Elmsly, Christopher John
core
Successful Treatment of Confirmed Naegleria fowleri Primary Amebic Meningoencephalitis
Emerging Infectious DiseasesPrimary amebic meningoencephalitis caused by Naegleria fowleri is a rare but nearly always fatal parasitic infection of the brain. Globally, few survivors have been reported, and the disease has no specific treatment.
A. Burki +6 more
semanticscholar +1 more source
bioRxiv, 2020 Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates >90%.
C. Rice +3 more
semanticscholar +1 more source