Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Alsam +32 more
core +1 more source
Seasonal Host Shifts for Legionella Within an Industrial Water‐Cooling System
Taxonomic profiling for Legionella (the causative agent of Legionnaires' disease) and protist hosts within a water cooling tower showed seasonal peaks for Legionella that were associated with taxonomic shifts in the protist community. Legionella frequency was tracked using amplicon sequencing (blue line) and serogroup profiling (red line).
Suzanne Crull +8 more
wiley +1 more source
The Genesis of the “Brain-Eating” Amoeba [PDF]
The Creator made all creatures, including amoebas, with variation and plasticity in their genome for global differences of climate, terrain, and environment. God made all creatures to multiply and fill the earth.
Augusta, Jonathan +2 more
core +1 more source
Detection and quantification of viable airborne bacteria and fungi using solid-phase cytometry [PDF]
This protocol describes the use of solid-phase cytometry for the enumeration of airborne bacteria and fungi. In contrast with conventional methods, accurate results can be obtained in real time, especially for air samples with low numbers of ...
Coenye, Tom, Nelis, Hans, Vanhee, Lies
core +1 more source
Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet +6 more
wiley +1 more source
Meningoencephalitis due to Naegleria fowleri in cattle in southern Brazil
Naegleria fowleri is a free-living amoeba commonly found in the environment, mainly in fresh water and soil. This protozoon is occasionally involved in cases of fatal central nervous system disease in humans and other animal species.
Luan Cleber Henker +6 more
doaj +1 more source
Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. [PDF]
Naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (PAM), in humans.
Wenxu Zhou +7 more
doaj +1 more source
The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]
The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
core
Encystation:the most prevalent and underinvestigated differentiation pathway of eukaryotes [PDF]
Not long ago, protists were considered one of four eukaryote kingdoms, but recent gene-based phylogenies show that they contribute to all nine eukaryote subdomains.
Schaap, Pauline, Schilde, Christina
core +2 more sources
Eukaryote‐Wide Distribution of a Family of Longin Domain‐Containing GAP Complexes for Small GTPases
The three longin domain‐containing GAP complexes ‐ CSW, folliculin, and GATOR1 ‐ have a sporadic but pan‐eukaryotic distribution and were likely already present in LECA in some form. Their catalytic longin domains contain highly conserved sequence motifs, some of which are shared with structurally similar proteins of Asgardarchaeota.
Anna M. G. Novák Vanclová +2 more
wiley +1 more source

