Results 21 to 30 of about 1,834 (177)
Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. [PDF]
PLoS Pathogens, 2018 Naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (PAM), in humans.
Wenxu Zhou +7 more
doaj +1 more source
BMC Genomics, 2018 Background Members of the genus Naegleria are free-living eukaryotes with the capability to transform from the amoeboid form into resting cysts or moving flagellates in response to environmental conditions.
Nicole Liechti +3 more
doaj +1 more source
Biology and pathogenesis of Naegleria fowleri [PDF]
Acta Tropica, 2016 Naegleria fowleri is a protist pathogen that can cause lethal brain infection. Despite decades of research, the mortality rate related with primary amoebic meningoencephalitis owing to N. fowleri remains more than 90%. The amoebae pass through the nose to enter the central nervous system killing the host within days, making it one of the deadliest ...
Ruqaiyyah, Siddiqui +3 more
openaire +2 more sources
Ultrastructure of Naegleria fowleri enflagellation [PDF]
Journal of Bacteriology, 1981 Amoebae of Naegleria fowleri nN68 became elongated flagellated cells 150 to 180 min after subculture to non-nutrient buffer. N. fowleri NF69 did not become elongated or flagellated under these conditions. Electron microscopic examination of N. fowleri confirmed that it is a typical eucaryotic protist with a distinct nuclear envelope and prominent ...
M, Patterson +3 more
openaire +2 more sources
Survey of Naegleria fowleri in geothermal recreational waters of Guadeloupe (French West Indies). [PDF]
PLoS ONE, 2013 In 2008 a fatal case of primary amoebic meningoencephalitis, due to the amoeboflagellate Naegleria fowleri, occurred in Guadeloupe, French West Indies, after a child swam in a bath fed with geothermal water.
Mirna Moussa +6 more
doaj +1 more source
A Fluorometric Assay for the In Vitro Evaluation of Activity against Naegleria fowleri Cysts
Microbiology Spectrum, 2022 Primary amoebic meningoencephalitis (PAM) is a lethal and rapid infection that affects the central nervous system and is caused by the free-living amoeba Naegleria fowleri.
Iñigo Arberas-Jiménez +5 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionFree-living amoebae of the Naegleria genus belong to the major protist clade Heterolobosea and are ubiquitously distributed in soil and freshwater habitats. Of the 47 Naegleria species described, N. fowleri is the only one being pathogenic to
Alexis Dereeper +9 more
doaj +1 more source
Data in Brief, 2018 The recombinant TvCP4 prepro region (ppTvCP4r) acts as an exogenous inhibitor of cathepsin L-like CPs from Trichomonas vaginalis (Cárdenas-Guerra et al., 2015 [1]). Here, we present the dataset of the trichomonad ppTvCP4r inhibitory effect against the CP
Rosa E. Cárdenas-Guerra +4 more
doaj +1 more source
Detection of Naegleria species in environmental samples from Peninsular Malaysia.
PLoS ONE, 2011 BackgroundIn Malaysia, researchers and medical practitioners are unfamiliar with Naegleria infections. Thus little is known about the existence of pathogenic Naegleria fowleri, and the resultant primary amoebic meningoencephalitis (PAM) is seldom ...
Init Ithoi +5 more
doaj +1 more source
Is Naegleria fowleri an Emerging Parasite? [PDF]
Trends in Parasitology, 2020 Naegleria fowleri causes an uncommon but deadly disease called primary amoebic meningoencephalitis (PAM). There has been an increase of reported PAM cases, particularly since 2000. Although water is the dominant route of transmission of PAM, infection through soil/dust is a possible alternative route.
Maciver, Sutherland +2 more
openaire +2 more sources