Results 11 to 20 of about 2,811 (206)
Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri [PDF]
BMC Biology, 2021 Background The opportunistic pathogen Naegleria fowleri establishes infection in the human brain, killing almost invariably within 2 weeks. The amoeba performs piece-meal ingestion, or trogocytosis, of brain material causing direct tissue damage and ...
Emily K. Herman +24 more
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Biology and pathogenesis of Naegleria fowleri [PDF]
Acta Tropica, 2016 Naegleria fowleri is a protist pathogen that can cause lethal brain infection. Despite decades of research, the mortality rate related with primary amoebic meningoencephalitis owing to N. fowleri remains more than 90%. The amoebae pass through the nose to enter the central nervous system killing the host within days, making it one of the deadliest ...
Ruqaiyyah, Siddiqui +3 more
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Primary Amoebic Meningoencephalitis in an Infant due to Naegleria fowleri [PDF]
Case Reports in Neurological Medicine, 2011 Primary amoebic meningoencephalitis (PAM) caused by free-living amebae Naegleria fowleri is a rare and fatal condition. A fatal case of primary amoebic meningoencephalitis was diagnosed in a 5-month-old infant who presented with the history of decrease ...
Vinay Khanna +8 more
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Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. [PDF]
PLoS Pathogens, 2018 Naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (PAM), in humans.
Wenxu Zhou +7 more
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International Journal of Infectious Diseases, 2018 Naegleria fowleri is the only Naegleria spp. known to cause an acute, fulminant, and rapidly fatal central nervous system infection in humans called primary amebic meningoencephalitis (PAM).
Ling-ling Zhang +6 more
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FatalNaegleria fowleriMeningoencephalitis, Italy [PDF]
Emerging Infectious Diseases, 2004 We report the first case of primary amebic meningoencephalitis in Italy, in a 9-year-old boy. Clinical course was fulminant, and diagnosis was made by identifying amebas in stained brain sections and by indirect immunofluorescence analysis. Naegleria fowleri was characterized as genotype I on the basis of polymerase chain reaction test results.
COGO, Paola +8 more
openaire +7 more sources
Journal of Parasitology ResearchFree-living amoebas are ubiquitous in distribution systems and recreational waters. Numerous studies have described the problem posed by their presence in the drinking water distribution systems of Lahore; however, very few studies have been done on ...
Ayesha Najam +4 more
doaj +2 more sources
Pharmacy Students’ Knowledge Assessment of Naegleria fowleri Infection [PDF]
Scientifica, 2016 A cross-sectional study was conducted from April to August 2015 to assess the knowledge of pharmacy students towards Naegleria fowleri infection.
Sadia Shakeel +2 more
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Emerging therapies against Naegleria fowleri [PDF]
Expert Opinion on Orphan DrugsIntroduction Naegleria fowleri is a free-living protist pathogen. Given the opportunity, it can produce infection of the central nervous system. It is distressing that the brain-eating amoebae, Naegleria fowleri remains one of the lethal parasites resulting almost always in death, despite advances in antimicrobial chemotherapy and supportive care ...
Ruqaiyyah Siddiqui +3 more
openaire +2 more sources
Scientific Reports, 2022 In the current study, we have systematically analysed the mitochondrial DNA (mtDNA) sequence of Naegleria fowleri (N. fowleri) isolate AY27, isolated from Karachi, Pakistan. The N.
Muhammad Aurongzeb +7 more
doaj +1 more source