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Repurposing of Nitroxoline as an Alternative Primary Amoebic Meningoencephalitis Treatment [PDF]

open access: yesAntibiotics, 2023
Among the pathogenic free-living amoebae (FLA), Naegleria fowleri is the etiological agent of a fatal disease known as primary amoebic meningoencephalitis (PAM).
Javier Chao-Pellicer   +6 more
doaj   +6 more sources

Case Report and Literature Review: Bacterial Meningoencephalitis or Not? Naegleria fowleri Related Primary Amoebic Meningoencephalitis in China [PDF]

open access: yesFrontiers in Pediatrics, 2022
In China, a 9-year-old boy was transferred to the hospital with fever, vomiting, and headache. The disease rapidly deteriorated into vague consciousness.
Wenjuan Zhou   +9 more
doaj   +4 more sources

Primary Amoebic Meningoencephalitis in an Iranian Infant [PDF]

open access: yesCase Reports in Medicine, 2012
Introduction. Naegleria fowleri, a free living amoeba, can cause devastating and deadly diseases in humans. This is the first report of primary amoebic meningoencephalitis from Iran. Case report.
Zahra Movahedi   +3 more
doaj   +6 more sources

Primary Amoebic Meningoencephalitis by Naegleria fowleri: Pathogenesis and Treatments [PDF]

open access: yesBiomolecules, 2021
Naegleria fowleri is a free-living amoeba (FLA) that is commonly known as the “brain-eating amoeba.” This parasite can invade the central nervous system (CNS), causing an acute and fulminating infection known as primary amoebic meningoencephalitis (PAM).
Andrea Güémez, Elisa García
doaj   +5 more sources

Diagnosis of primary amoebic meningoencephalitis by metagenomic next-generation sequencing: A case report [PDF]

open access: yesOpen Life Sciences, 2023
Primary amoebic meningoencephalitis (PAM) caused by Naegleria fowleri is a fatal infection with a mortality rate of more than 95%, despite advances in antimicrobial chemotherapy and supportive care.
Che Xiujuan   +4 more
doaj   +3 more sources

Primary amoebic meningoencephalitis caused by Naegleria fowleri: an old enemy presenting new challenges. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
First discovered in 1899, Naegleria fowleri is a protist pathogen, known to infect the central nervous system and produce primary amoebic meningoencephalitis.
Ruqaiyyah Siddiqui, Naveed Ahmed Khan
doaj   +4 more sources

A primary amoebic meningoencephalitis case suspected to be infected by indoor swimming, China, 2024 [PDF]

open access: yesFrontiers in Medicine
IntroductionNaegleria fowleri causes Primary Amoebic Meningoencephalitis (PAM), an unusual but fatal disease. Swimming in wild freshwater is commonly regarded as the primary cause of infection.
Junfan Li   +10 more
doaj   +4 more sources

Primary Amoebic Meningoencephalitis in an Infant due to Naegleria fowleri [PDF]

open access: yesCase Reports in Neurological Medicine, 2011
Primary amoebic meningoencephalitis (PAM) caused by free-living amebae Naegleria fowleri is a rare and fatal condition. A fatal case of primary amoebic meningoencephalitis was diagnosed in a 5-month-old infant who presented with the history of decrease ...
Vinay Khanna   +8 more
doaj   +4 more sources

CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2017
Primary Amoebic Meningoencephalitis (PAM) is caused by Naegleria fowleri, a free-living amoeba that occasionally infects humans. While considered "rare" (but likely underreported) the high mortality rate and lack of established success in treatment makes
Anjan Debnath   +9 more
doaj   +4 more sources

Primary amoebic meningoencephalitis. [PDF]

open access: yesJ Neurosci Rural Pract, 2015
Primary amoebic meningoencephalitis due to free living amoeba, also called 'brain eating amoeba', Naegleria fowleri, was detected in retroviral disease patient of 40 years who has history of using well water. Patient was admitted with severe headache, fever intermittent, nausea, vomiting and slurring of speech. CT scan and MRI scan findings were normal.
Shrestha GS   +7 more
europepmc   +5 more sources

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