Results 31 to 40 of about 1,492 (144)

Primary Amoebic Meningoencephalitis [PDF]

open access: yesCRC Critical Reviews in Clinical Laboratory Sciences, 1970
(1972). Primary Amoebic Meningoencephalitis. CRC Critical Reviews in Clinical Laboratory Sciences: Vol. 3, No. 2, pp. 163-192.
  +7 more sources

Mannich‐Type Condensation and Domino Quinazolinone‐Amidine Rearrangement Affords Ring‐Fused Mackinazolinones with Anti‐Amoebic Activity

open access: yesAdvanced Synthesis &Catalysis, Volume 365, Issue 24, Page 4567-4575, December 19, 2023., 2023
Abstract A three‐step synthesis of anti‐amoebic, ring‐fused mackinazolinones has been developed. A Mannich‐type reaction between quinazolin‐4‐ones and N‐Cbz propanal in the presence of AgOTf afforded quinazolinones (19–94% isolated yield) bearing a newly formed heterocycle with an alkylamine appendage that, upon N‐Cbz deprotection and basification ...
Matthew S. Lish   +5 more
wiley   +1 more source

Identification and characterization of novel marine oxasqualenoid yucatecone against Naegleria fowleri

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2023
Naegleria fowleri is an opportunistic protozoan, belonging to the free-living amoeba group, that can be found in warm water bodies. It is causative agent the primary amoebic meningoencephalitis, a fulminant disease with a rapid progression that affects ...
Iñigo Arberas-Jiménez   +10 more
doaj   +1 more source

Primary amoebic meningoencephalitis. [PDF]

open access: yesArchives of Disease in Childhood, 1981
The third case in the UK of primary amoebic meningoencephalitis is reported; it affected an 11-year-old girl. Six days before admission the girl had swum in a pool fed by hot spring water in which the causative agent Naegleria fowleri was found. Early treatment with amphotericin B would seem to offer the only hope of recovery in this almost uniformly ...
A R, Cain   +3 more
openaire   +2 more sources

Waterborne parasites in Uganda: A survey in Queen Elizabeth Protected Area

open access: yesPublic Health Challenges, Volume 2, Issue 4, December 2023., 2023
As water has a multitude of functions, encompassing culinary, hygienic and recreational applications, studies looking at potentially pathogenic waterborne pathogens are crucial in order to prevent disease spread to rural populations and tourists. This study aimed at detecting protozoan trophozoites/cysts, and helminth eggs in environmental and piped ...
Celsus Sente   +6 more
wiley   +1 more source

Guidelines for the purification and characterization of extracellular vesicles of parasites

open access: yesJournal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra   +30 more
wiley   +1 more source

Identifying group‐specific primers for environmental Heterolobosa by high‐throughput sequencing

open access: yesMicrobial Biotechnology, Volume 15, Issue 9, Page 2476-2487, September 2022., 2022
In this work, we designed and tested new primer pair that helps to target Heterolobosea, a group of protist that is often neglected and undercovered in conventional high throughput sequencing approaches Summary Diversity of Heterolobosea (Excavata) in environments is poorly understood despite their ecological occurrence and health‐associated risk ...
Vincent Delafont   +5 more
wiley   +1 more source

Structural informatics approach for designing an epitope-based vaccine against the brain-eating Naegleria fowleri

open access: yesFrontiers in Immunology, 2023
Primary Amoebic Meningoencephalitis (PAM), a severe lethal brain disease, is caused by a parasite, Naegleria fowleri, also known as the “brain-eating amoeba”. The chances of a patient’s recovery after being affected by this parasite are very low. Only 5%
Asifa Sarfraz   +11 more
doaj   +1 more source

Primary amoebic meningoencephalitis in Britain [PDF]

open access: yesBMJ, 1969
Primary amoebic meningoencephalitis is caused by amoebae of the genera Naegleria and Hartmannella (Acanthamoeba), which ordinarily are free-living saprophytes. The infection may be acquired from fresh water-for example, while bathing-the amoebae invading the nasal mucosa and reaching the meninges and brain along the olfactory nerve filaments.
openaire   +2 more sources

Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris

open access: yesAntibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui   +7 more
doaj   +1 more source

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