Results 11 to 20 of about 4,506,322 (141)

Primary Amoebic Meningoencephalitis in an Infant due to Naegleria fowleri [PDF]

Case Reports in Neurological Medicine, 2011
Primary amoebic meningoencephalitis (PAM) caused by free-living amebae Naegleria fowleri is a rare and fatal condition. A fatal case of primary amoebic meningoencephalitis was diagnosed in a 5-month-old infant who presented with the history of decrease ...
Vinay Khanna, Ruchee Khanna, Shrikiran Hebbar, V. Shashidhar, Sunil Mundkar, Frenil Munim, Karthick Annamalai, Deepak Nayak, Chiranjay Mukhopadhayay   +8 more
doaj   +2 more sources

Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis. [PDF]

J Infect Dis, 2019
Naegleria fowleri is the causative agent of primary amoebic meningoencephalitis (PAM), which is fatal in \u3e97% of cases. In this study, we aimed to identify new, rapidly acting drugs to increase survival rates.
Colon BL, Rice CA, Guy RK, Kyle DE.
europepmc   +3 more sources

Evaluating the Drinking Water Distribution System of Lahore for Free-Living Amoebas, Particularly Naegleria spp.

Journal of Parasitology Research
Free-living amoebas are ubiquitous in distribution systems and recreational waters. Numerous studies have described the problem posed by their presence in the drinking water distribution systems of Lahore; however, very few studies have been done on ...
Ayesha Najam, Sana Ullah Iqbal, Waqas Ahmed, Rabia Tanvir, Haroon Akbar   +4 more
doaj   +2 more sources

Nanoparticle-Terpene Fusion: A Game-Changer in Combating Primary Amoebic Meningoencephalitis Caused by Naegleria fowleri [PDF]

ACS Omega
Pathogenic Naegleria fowleri (N. fowleri) are opportunistic free-living amoebae and are the causative agents of a very rare but severe brain infection called primary amoebic meningoencephalitis (PAM).
Kavitha Rajendran, Usman Ahmed, Alexia Chloe Meunier, Mohd Farooq Shaikh, Ruqaiyyah Siddiqui, Ayaz Anwar   +5 more
doaj   +3 more sources

Ginsenosides Rb3 and Rc Exhibit Anti-Amoebic Activities Against Naegleria fowleri, the Etiological Agent of Primary Amoebic Meningoencephalitis [PDF]

Pharmaceuticals
Background/Objectives: Naegleria fowleri is an opportunistic pathogen causing primary amoebic meningoencephalitis (PAM), a fatal neuroinflammatory disease with a high mortality rate of over 97%, in humans.
Thu Hằng Nguyễn, Hương Giang Lê, Tuấn Cường Võ, Minkyoung Cho, Byoung-Kuk Na   +4 more
doaj   +2 more sources

Primary amoebic meningoencephalitis: first reported case from Rohtak, North India [PDF]

Brazilian Journal of Infectious Diseases
A fatal case of primary amoebic encephalitis (PAM) in a 20 year old boy, a proven case of acute leukemic leukemia (ALL) type L2, in remission is described. No history of swimming could be elicited.
Naveen Gupta, Hemlata Bhaskar, Shalini Duggal, Pratap S. Ghalaut, Shailja Kundra, Des R. Arora   +5 more
doaj   +2 more sources

A case of Naegleria fowleri related primary amoebic meningoencephalitis in China diagnosed by next-generation sequencing [PDF]

BMC Infectious Diseases, 2018
Background Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare protozoan infectious disease in China. A fatality rate of over 95% had been reported due to extremely rapid disease progression in the USA and other countries ...
Qiang Wang, Jianming Li, Jingkai Ji, Liuqing Yang, Li Chen, Rongrong Zhou, Yang Yang, Haixia Zheng, Jing Yuan, Liqiang Li, Yuhai Bi, George F. Gao, Jinmin Ma, Yingxia Liu   +13 more
doaj   +2 more sources

Fatal brain infection in early life: primary amoebic meningoencephalitis caused by Naegleria fowleri in neonates and infants [PDF]

BMC Infectious Diseases
Background Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare but often fatal central nervous system infection that mimics bacterial meningitis.
Javad Mahdavi, Setareh Pirayeshfar, Aref Shariati, Reza Ghasemikhah   +3 more
doaj   +2 more sources

CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). [PDF]

PLoS Neglected Tropical Diseases, 2017
Primary Amoebic Meningoencephalitis (PAM) is caused by Naegleria fowleri, a free-living amoeba that occasionally infects humans. While considered "rare" (but likely underreported) the high mortality rate and lack of established success in treatment makes
Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podust   +9 more
doaj   +2 more sources

Fatal Primary Amoebic Meningoencephalitis in Coastal Areas of North China in an Immunocompetent Patient: A Case Report and Literature Review [PDF]

Infection and Drug Resistance
Qian Li Wang,1,* Sheng Nan Teng,1,* Xiao Jing Zhang,2 Yu Xin Guo,2 Yang Kong,1 Xing Han Tian,1 Yi Zhang1,3 1Department of Critical Care Medicine, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, Shandong, People’s ...
Wang QL, Teng SN, Zhang XJ, Guo YX, Kong Y, Tian XH, Zhang Y   +6 more
doaj   +2 more sources