Results 51 to 60 of about 1,492 (144)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Emerging Infectious DiseasesWe investigated a fatal case of primary amoebic meningoencephalitis from an indoor surfing center in Taiwan. The case was detected through encephalitis syndromic surveillance.
Hsin-Yi Wei +6 more
doaj +1 more source
Archives of Pharmacy Practice, 2016 Objective: This study was aimed at gathering all the data related to Naegleria fowleri resulted primary amoebic meningoencephalitis (PAM) deaths in Pakistan and present it in a dataset, conduct statistical analysis to report any significant finding and ...
Atta Abbas Naqvi +4 more
doaj +1 more source
Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.Naegleria fowleri, the brain‐eating ameba, causes primary amebic meningoencephalitis (PAM), a fatal infectious disease that affects the central nervous system (CNS). We aimed to evaluate the functions and potential drugs targeting PAM using text mining and bioinformatics analyses.
Eun Jung Sohn +3 more
wiley +1 more source
Cellular Coordination of Transcription Factors and Regulatory Genes for Cryptococcal Virulence
Cellular Microbiology, Volume 2026, Issue 1, 2026.Cryptococcus neoformans is an opportunistic pathogen belonging to the family Cryptococcaceae, capable of causing systemic and invasive fungal infections in humans and animals. The infection caused by Cryptococcus is lethal primarily in immunocompromised individuals due to the overwhelming expression of virulence factors that drive cryptococcosis in ...
Olufemi S. Folorunso +2 more
wiley +1 more source
Cancer Reports, Volume 8, Issue 8, August 2025.ABSTRACT Background The PI3K/Akt/mTOR signaling pathway is commonly deregulated in different types of cancers, contributing to tumor proliferation, persistence, and resistance to treatment. Akt1, a crucial kinase within this pathway, plays a critical role in tumor progression and the occurrence of therapeutic resistance.
Shokoofeh Jamshidi +4 more
wiley +1 more source
Drugs used for the treatment of cerebral and disseminated infections caused by free‐living amoebae
Clinical and Translational Science, 2021 Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become pathogenic and ...
Alexandre Taravaud +3 more
doaj +1 more source
Effect of splenectomy on development of primary amoebic meningoencephalitis
The Korean Journal of Parasitology, 1985 To elucidate the effect of splenectomy on the development of experimental primary amoebic meningoencephalitis in mice, the death rate and survival time of mice infected intranasally with Naegleria fowleri trophozoites 5 x 10(4) cultivated in CGVS medium were compared according to the age when splenectomy was done, and post-operation until experimental ...
Ho Joon, Shin +2 more
openaire +2 more sources
Primary amoebic meningoencephalitis in North Queensland: the paediatric experience [PDF]
Medical Journal of Australia, 2016 Primary amoebic meningoencephalitis (PAM) is a fulminant, diffuse haemorrhagic meningoencephalitis caused by Naegleria fowleri, with an almost invariably fatal outcome. In Australia and the developed world, PAM remains a rare disease, although it is very likely that large numbers of cases go undetected in developing countries. N.
Nicholls, Claire L. +6 more
openaire +4 more sources