Results 71 to 80 of about 1,492 (144)

The epidemiology of primary amoebic meningoencephalitis in the USA, 1962–2008

Epidemiology and Infection, 2009
SUMMARYNaegleria fowleri, a free-living, thermophilic amoeba ubiquitous in the environment, causes primary amoebic meningoencephalitis (PAM), a rare but nearly always fatal disease of the central nervous system. While case reports of PAM have been documented worldwide, very few individuals have been diagnosed with PAM despite the vast number of people ...
J S, Yoder, B A, Eddy, G S, Visvesvara, L, Capewell, M J, Beach   +4 more
openaire   +2 more sources

Discovery of repurposing drug candidates for the treatment of diseases caused by pathogenic free-living amoebae.

PLoS Neglected Tropical Diseases, 2020
Diseases caused by pathogenic free-living amoebae include primary amoebic meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis (Acanthamoeba spp.), Acanthamoeba keratitis, and Balamuthia amoebic encephalitis (Balamuthia ...
Christopher A Rice, Beatrice L Colon, Emily Chen, Mitchell V Hull, Dennis E Kyle   +4 more
doaj   +1 more source

Integrated track of nano-informatics coupling with the enrichment concept in developing a novel nanoparticle targeting ERK protein in Naegleria fowleri

Open Chemistry
Naegleria fowleri is a free-living amoeba that causes primary amoebic meningoencephalitis. Despite combination drug therapies, N. fowleri is not sensitive to current drug therapies, contributing to the pathogen’s mortality rate of 98%. To enable rational
Naveed Muhammad, ul Ain Noor, Aziz Tariq, Saleem Ayesha, Shabbir Muhammad Aqib, Khan Ayaz Ali, Albekairi Thamer H.   +6 more
doaj   +1 more source

Brain-Eating Amoeba Meets Plant Defense: In Vitro and In Silico Evaluation of Malabaricones as Potent Anti-Naegleria fowleri Agents

Progress in Microbes and Molecular Biology
Naegleria fowleri (N. fowleri) is a thermophilic, free-living amoeba that causes primary amoebic meningoencephalitis (PAM), a rapidly fatal brain infection with a mortality rate exceeding 97%.
Kavitha Rajendran, Lemmuel Tayo, Marineil Gomez, Devandran Apparasamy, Haema Thevanayagam, Shealtiel William Chan, Ryan Christian Mailem, Regine Menente, Catherine Joyce Rueda, Yasodha Sivasothy, Muhamad Aqmal Othman, Usman Ahmed, Niwasini Krishna Kumar, Chris Izaak Jones, Ayaz Anwar   +14 more
doaj   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

ePosters Virtual

European Journal of Neurology, Volume 31, Issue S1, June 2024.
wiley   +1 more source

ISEV2024 Abstract Book

Journal of Extracellular Vesicles, Volume 13, Issue S1, May 2024.
wiley   +1 more source

A pediatric case of primary amoebic meningoencephalitis due to Naegleria fowleri diagnosed by next-generation sequencing of cerebrospinal fluid and blood samples. [PDF]

BMC Infect Dis, 2021
Huang S, Liang X, Han Y, Zhang Y, Li X, Yang Z.   +5 more
europepmc   +1 more source

Potential Application of Vaporized Drugs via Nasal Inhalers to Prevent Mortality and Central Nervous System Damage Caused by Primary Amoebic Meningoencephalitis Due to Naegleria fowleri. [PDF]

ACS Pharmacol Transl Sci, 2021
Siddiqui R, Abouleish MY, Khamis M, Ibrahim T, Khan NA.   +4 more
europepmc   +1 more source

Fatal brain infection in early life: primary amoebic meningoencephalitis caused by Naegleria fowleri in neonates and infants

BMC Infectious Diseases
Background Primary amoebic meningoencephalitis (PAM), caused by Naegleria fowleri, is a rare but often fatal central nervous system infection that mimics bacterial meningitis.
Javad Mahdavi, Setareh Pirayeshfar, Aref Shariati, Reza Ghasemikhah   +3 more
doaj   +1 more source