Results 41 to 50 of about 1,834 (177)

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

Cytoskeleton, Volume 83, Issue 7, Page 457-465, July 2026.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, Volume 600, Issue 5, Page 591-611, March 2026.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Identification of Potential Therapeutic Agents for Primary Amebic Meningoencephalitis Using Text Mining and Bioinformatics Analyses

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Naegleria fowleri, the brain‐eating ameba, causes primary amebic meningoencephalitis (PAM), a fatal infectious disease that affects the central nervous system (CNS). We aimed to evaluate the functions and potential drugs targeting PAM using text mining and bioinformatics analyses.
Eun Jung Sohn, Hyeonseo Jo, Kun Taek Park, Andrey Elchaninov   +3 more
wiley   +1 more source

Naegleria fowleri and Naegleria gruberi 20S proteasome: identification and characterization

European Journal of Cell Biology, 2020
The Naegleria are ubiquitous free-living amoebae and are characterized by the presence of three phases in their biological cycle: trophozoite, cyst and flagellate. Of this genus, only Naegleria fowleri has been reported as pathogenic to humans. The proteasome is a multi-catalytic complex and is considered to be the most important structure responsible ...
Paula, Guzmán-Téllez, Diana, Martínez-Valencia, Angélica, Silva-Olivares, Rosa M, Del Ángel, Jesús, Serrano-Luna, Mineko, Shibayama   +5 more
openaire   +2 more sources

Agglutination of Naegleria fowleri and Naegleria gruberi by antibodies in human serum [PDF]

Journal of Clinical Microbiology, 1983
The capability of serum samples from 423 human subjects to agglutinate rounded cells of Naegleria fowleri nN68 was assessed. Sera from the umbilical cords of seven infants failed to agglutinate N. fowleri cells. The median agglutination titer was 1:4 for sera from children through age 4 years, 1:8 for sera from juveniles 5 to 15 years of age, and 1:16 ...
M F, Reilly, F, Marciano-Cabral, D W, Bradley, S G, Bradley   +3 more
openaire   +2 more sources

GalNAc Carbohydrate Prevents the Formation of Neutrophil Extracellular Traps and Increase Myeloperoxidase Enzyme Activity in Interactions of Neutrophils and Entamoeba histolytica Preincubated With GalNAc

BioMed Research International, Volume 2026, Issue 1, 2026.
During amoebic infection, neutrophils are the first cells of the immune system to interact with trophozoites of Entamoeba histolytica, initiating amoebicidal activity. Different lectins and carbohydrates can participate in the mechanism of adhesion between E.
David Levaro-Loquio, Andrea Cruz-Baquero, Germán Higuera-Martínez, José De Jesús Serrano-Luna, Arturo Contis-Montes de Oca, Edgar Abarca-Rojano, Ivonne Maciel Arciniega-Martínez, Aldo Arturo Reséndiz-Albor, Judith Pacheco-Yépez, Edilene O. Silva   +9 more
wiley   +1 more source

Agglutination of Naegleria fowleri by Human Serum

Experimental Biology and Medicine, 1982
AbstractThe capability of 154 serum samples from pediatric outpatients and 101 samples from adults to agglutinate amoebae of Naegleria fowleri nN68 was assessed. Sera from all 19 infants tested had an agglutination titer of 1:4 or less; sera of toddlers had a median agglutination titer of 1:8 and those of adults, 1:16. Only 13 of 154 serum samples from
M F, Reilly, M K, Bradley, S G, Bradley
openaire   +2 more sources

Detection of Microbial Contaminants in Water: Conventional Methods, Pragmatic Alternatives, and Nanosensing Techniques

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Conventional culture and immunological methods of detecting bacterial water contaminants have some limitations. There are alternative pragmatic methods which are more efficient and faster in the detection of bacteria in water, especially nanosensors. ABSTRACT The complexities of microbial detection and conventional enumeration necessitates the adoption
Adeyemi O. Adeeyo, Joshua N. Edokpayi, Mercy A. Alabi, Joshua A. Oyetade, Eunice Ubomba‐Jaswa, Penny Jaca, Rachel Makungo   +6 more
wiley   +1 more source

FatalNaegleria fowleriMeningoencephalitis, Italy

Emerging Infectious Diseases, 2004
We report the first case of primary amebic meningoencephalitis in Italy, in a 9-year-old boy. Clinical course was fulminant, and diagnosis was made by identifying amebas in stained brain sections and by indirect immunofluorescence analysis. Naegleria fowleri was characterized as genotype I on the basis of polymerase chain reaction test results.
COGO, Paola, Scaglia, Massimo, Gatti, Simonetta, Rossetti, Flavio, Alaggio, Rita, Laverda, Anna Maria, Zhou, Ling, Xiao, Lihua, Visvesvara, Govinda S.   +8 more
openaire   +6 more sources