Results 61 to 70 of about 4,186 (166)

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes

open access: yesMolecular Microbiology, Volume 124, Issue 1, Page 54-65, July 2025.
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet   +6 more
wiley   +1 more source

Nanopore sequencing improves the draft genome of the human pathogenic amoeba Naegleria fowleri. [PDF]

open access: yes, 2019
Naegleria fowleri is an environmental protist found in soil and warm freshwater sources worldwide and is known for its ability to infect humans and causing a rapid and mostly fatal primary amoebic meningoencephalitis.
Wittwer, Matthias   +3 more
core   +2 more sources

Lethal encounters: The evolving spectrum of amoebic meningoencephalitis

open access: yesIDCases, 2019
The free-living amoebae are thermophilic organisms that may play an increasing role among diseases of a warming world. They are uncommon, accidental, yet high consequence pathogens, with differing pathologic syndromes.
Sandra G. Gompf, Cristina Garcia
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

open access: yesiLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian   +7 more
wiley   +1 more source

Emerging therapies against Naegleria fowleri [PDF]

open access: yes
Introduction: Naegleria fowleri is a free-living protist pathogen. Given the opportunity, it can produce infection of the central nervous system. It is distressing that the brain-eating amoebae, Naegleria fowleri remains one of the lethal parasites ...
Lloyd, David   +4 more
core   +1 more source

Meningoencefalitis amebiana primaria por Naegleria fowleri [PDF]

open access: yes, 2023
Las Amebas de Vida Libre (AVL) son protozoos que viven libremente en el ambiente. Se alimentan de bacterias y otros microorganismos. Presentan estadios quísticos (resistencia) y trofozoítos (reproducción).
Costamagna, Sixto Raúl
core  

A preliminary study on Naegleria species in water bodies of Kurunegala district, Sri Lanka

open access: yesSri Lankan Journal of Infectious Diseases, 2018
Introduction and Objective: Species belonging to the genus Naegleria are free-living ubiquitous protozoa. They have been isolated from most regions of the world. N.
JANS Gunarathna   +2 more
doaj   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou   +18 more
wiley   +1 more source

In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri

open access: yesFrontiers in Microbiology, 2018
Primary amebic meningoencephalitis (PAM) is a fatal infection caused by the free-living ameba Naegleria fowleri, popularly known as the “brain-eating ameba.” The drugs of choice in treating PAM are the antifungal amphotericin B and an antileishmanial ...
Anjan Debnath   +5 more
doaj   +1 more source

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

open access: yesInternational Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham   +4 more
wiley   +1 more source

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