Results 61 to 70 of about 1,834 (177)
Cell Proliferation, Volume 58, Issue 4, April 2025.This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou +18 more
wiley +1 more source
Lethal encounters: The evolving spectrum of amoebic meningoencephalitis
IDCases, 2019 The free-living amoebae are thermophilic organisms that may play an increasing role among diseases of a warming world. They are uncommon, accidental, yet high consequence pathogens, with differing pathologic syndromes.
Sandra G. Gompf, Cristina Garcia
doaj +1 more source
International Journal of Pediatrics, Volume 2025, Issue 1, 2025.Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham +4 more
wiley +1 more source
Pharmacy Students’ Knowledge Assessment of Naegleria fowleri Infection
Scientifica, 2016 A cross-sectional study was conducted from April to August 2015 to assess the knowledge of pharmacy students towards Naegleria fowleri infection.
Sadia Shakeel +2 more
doaj +1 more source
A preliminary study on Naegleria species in water bodies of Kurunegala district, Sri Lanka
Sri Lankan Journal of Infectious Diseases, 2018 Introduction and Objective: Species belonging to the genus Naegleria are free-living ubiquitous protozoa. They have been isolated from most regions of the world. N.
JANS Gunarathna +2 more
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Experimental Infection of Naegleria fowleri in Mice
Journal of the Japanese Association for Infectious Diseases, 1998 Ten SPF mice (ddY, 4w-old, female) were infected by nasal instillation with an isolate of Naegleria fowleri that was first isolated from a patient with primary amoebic meningoencephalitis (PAM) in Japan. Of these mice, 2 showed clinical signs typical for PAM on the 4th day.
KUROKI, Toshiro +6 more
openaire +3 more sources
In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri
Frontiers in Microbiology, 2018 Primary amebic meningoencephalitis (PAM) is a fatal infection caused by the free-living ameba Naegleria fowleri, popularly known as the “brain-eating ameba.” The drugs of choice in treating PAM are the antifungal amphotericin B and an antileishmanial ...
Anjan Debnath +5 more
doaj +1 more source
Diabetes, Obesity and Metabolism, Volume 26, Issue 9, Page 3491-3500, September 2024.Abstract Obesity has become a major global problem that significantly confers an increased risk of developing life‐threatening complications, including type 2 diabetes mellitus, fatty liver disease and cardiovascular diseases. Protein arginine methyltransferases (PRMTs) are enzymes that catalyse the methylation of target proteins.
Xiaolei Xuan +6 more
wiley +1 more source
Identification of Immunogenic Antigens of Naegleria fowleri Adjuvanted by Cholera Toxin
Pathogens, 2020 The intranasal administration of Naegleria fowleri lysates plus cholera toxin (CT) increases protection against N. fowleri meningoencephalitis in mice, suggesting that humoral immune response mediated by antibodies is crucial to induce protection against
Saúl Rojas-Hernández +7 more
doaj +1 more source
Frontiers in MicrobiologyNaegleria fowleri is the causative agent of primary amoebic meningoencephalitis, a rapid and acute infection of the central nervous system with a fatal outcome in >97% of cases. Due to the infrequent report of cases and diagnostic gaps that hinder the
Lissette Retana Moreira +11 more
doaj +1 more source