Results 71 to 80 of about 4,641 (223)

FatalNaegleria fowleriMeningoencephalitis, Italy

Emerging Infectious Diseases, 2004
We report the first case of primary amebic meningoencephalitis in Italy, in a 9-year-old boy. Clinical course was fulminant, and diagnosis was made by identifying amebas in stained brain sections and by indirect immunofluorescence analysis. Naegleria fowleri was characterized as genotype I on the basis of polymerase chain reaction test results.
COGO, Paola, Scaglia, Massimo, Gatti, Simonetta, Rossetti, Flavio, Alaggio, Rita, Laverda, Anna Maria, Zhou, Ling, Xiao, Lihua, Visvesvara, Govinda S.   +8 more
openaire   +6 more sources

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes

Molecular Microbiology, Volume 124, Issue 1, Page 54-65, July 2025.
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet, Raphael Munoz‐Ruiz, Imen Ayadi, Alixia Bourbon, Erwann Pain, Joseph Oddy, Pierre Cosson   +6 more
wiley   +1 more source

Naegleria Fowleri - Prevention is the best cure

Journal of the Pakistan Medical Association, 2023
Respected Editor, With the temperatures rising every summer and the quality of water deteriorating in Pakistan and specially Karachi the ‘brain-eating amoeba’ Naegleria fowleri was on rise during this summer too. 6 cases of primary amebic meningoencephalitis (PAM) caused by N.
openaire   +2 more sources

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

A giant virus infecting the amoeboflagellate Naegleria

Nature Communications
Giant viruses (Nucleocytoviricota) are significant lethality agents of various eukaryotic hosts. Although metagenomics indicates their ubiquitous distribution, available giant virus isolates are restricted to a very small number of protist and algal ...
Patrick Arthofer, Florian Panhölzl, Vincent Delafont, Alban Hay, Siegfried Reipert, Norbert Cyran, Stefanie Wienkoop, Anouk Willemsen, Ines Sifaoui, Iñigo Arberas-Jiménez, Frederik Schulz, Jacob Lorenzo-Morales, Matthias Horn   +12 more
doaj   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

Cell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou, Yifeng Chen, Yuhao Ba, Hui Xu, Anning Zuo, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Yuqing Ren, Peng Luo, Quan Cheng, Lulu Zuo, Shanshan Zhu, Xing Zhou, Chuhan Zhang, Yukang Chen, Xinwei Han, Teng Pan, Zaoqu Liu   +18 more
wiley   +1 more source

Detection of protozoan hosts for Legionella pneumophila in engineered water systems by using a biofilm batch test [PDF]

, 2010
Legionella pneumophila proliferates in aquatic habitats within free-living protozoa, 17 species of which have been identified as hosts by using in vitro experiments. The present study aimed at identifying protozoan hosts for L.
Valster, R.M., Wullings, B.A., Kooij, D., van der   +2 more
core   +2 more sources

Clinical, Laboratory Characteristics, and Microorganism Infection Status in Neonates With Meningitis in Vietnam: A Cross‐Sectional Descriptive Study

International Journal of Pediatrics, Volume 2025, Issue 1, 2025.
Objective This study is aimed at describing the clinical and laboratory characteristics and determining the prevalence of microbial pathogens causing neonatal meningitis detected by cerebrospinal fluid (CSF) real‐time polymerase chain reaction (PCR). Materials and Methods A cross‐sectional descriptive study was conducted on 55 neonates diagnosed with ...
Tho Kieu Anh Pham, Binh Thien Nguyen, Phuong Minh Nguyen, Khai Quang Tran, Nikhat Kaura   +4 more
wiley   +1 more source

Induced encystment improves resistance to preservation and storage of Acanthamoeba castellanii [PDF]

, 2008
Several conditions that allow the preservation, storage and rapid, efficient recovery of viable Acanthamoeba castellanii organisms were investigated. The viability of trophozoites (as determined by time to confluence) significantly declined over a period
Campbell, S. J., Henriquez, F. L., Ingram, P. R., Roberts, C. W.   +3 more
core   +1 more source

Experimental meningoencephalitis by Naegleria fowleri in mice

The Korean Journal of Parasitology, 1984
Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size of N. fowleri trophozoite. In this paper, the effect of these factors on PAM development of mouse was studied. N.
Myoung Hee, Ahn, Kyung Il, Im
openaire   +2 more sources