Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.Naegleria fowleri, the brain‐eating ameba, causes primary amebic meningoencephalitis (PAM), a fatal infectious disease that affects the central nervous system (CNS). We aimed to evaluate the functions and potential drugs targeting PAM using text mining and bioinformatics analyses.
Eun Jung Sohn +3 more
wiley +1 more source
The in vitro and in vivo testing of chemotherapeutic agents against pathogenic free living amebae : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University, Palmerston North, New Zealand. [PDF]
, 1980 During the last ten years, there has been an increasing awareness of sporadic cases of Primary Amoebic Meningo-encephalitis (PAM) affecting primarily younger age groups and appearing in an acute fulminant form. The earliest positive case (Willaert, 1974)
Elmsly, Christopher John
core
BioMed Research International, Volume 2026, Issue 1, 2026.During amoebic infection, neutrophils are the first cells of the immune system to interact with trophozoites of Entamoeba histolytica, initiating amoebicidal activity. Different lectins and carbohydrates can participate in the mechanism of adhesion between E.
David Levaro-Loquio +9 more
wiley +1 more source
Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]
, 2004 The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Alsam +32 more
core +1 more source
MicrobiologyOpen, Volume 14, Issue 6, December 2025.Conventional culture and immunological methods of detecting bacterial water contaminants have some limitations. There are alternative pragmatic methods which are more efficient and faster in the detection of bacteria in water, especially nanosensors. ABSTRACT The complexities of microbial detection and conventional enumeration necessitates the adoption
Adeyemi O. Adeeyo +6 more
wiley +1 more source
The susceptibility of pathogenic free-living amebae to chemotherapeutic agents : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]
, 1979 The treatment of infections caused by pathogenic free-living amebae (PFLA) has, until only recently, been far from successful. The continued screening of chemotherapeutic agents against amebae of the genera Naegleria and Acanthamoeba is therefore of the ...
Donald, Jennifer Jane
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Chamigrane-Type Sesquiterpenes from Laurencia dendroidea as Lead Compounds against Naegleria fowleri
Marine Drugs, 2023 Naegleria fowleri is an opportunistic protozoon that can be found in warm water bodies. It is the causative agent of the primary amoebic meningoencephalitis.
Iñigo Arberas-Jiménez +8 more
doaj +1 more source
Primary Amoebic (Naegleria fowleri) Meningoencephalitis Presenting as Status Epilepticus [PDF]
, 2011 Primary amebic meningoencephalitis (PAM) is a rare entity. Usual presenting features are fever, headache and seizures with meningeal signs and this disease carries high mortality rate.
Bharti, V +5 more
core +1 more source
Primary amoebic meningoencephalitis: amoebicidal effects of clinically approved drugs against Naegleria fowleri [PDF]
, 2014 Here we tested the effects of clinically approved drugs targeting vital cellular receptors and biochemical pathways against Naegleria fowleri. For the first time, our findings revealed that digoxin and procyclidine showed potent amoebicidal effects as no
Baig, Abdul +2 more
core +1 more source
Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.Free‐living amoebae and bacteria were monitored along a salinity gradient over 1 year. Naegleria and Vibrio were the most represented genera, with salinity and dissolved oxygen identified as key factors structuring amoebae diversity and associated bacterial communities under changing environmental conditions.
Gaëlle Bednarek +5 more
wiley +1 more source