Results 51 to 60 of about 1,834 (177)

Naegleria Fowleri - Prevention is the best cure

Journal of the Pakistan Medical Association, 2023
Respected Editor, With the temperatures rising every summer and the quality of water deteriorating in Pakistan and specially Karachi the ‘brain-eating amoeba’ Naegleria fowleri was on rise during this summer too. 6 cases of primary amebic meningoencephalitis (PAM) caused by N.
openaire   +2 more sources

A giant virus infecting the amoeboflagellate Naegleria

Nature Communications
Giant viruses (Nucleocytoviricota) are significant lethality agents of various eukaryotic hosts. Although metagenomics indicates their ubiquitous distribution, available giant virus isolates are restricted to a very small number of protist and algal ...
Patrick Arthofer, Florian Panhölzl, Vincent Delafont, Alban Hay, Siegfried Reipert, Norbert Cyran, Stefanie Wienkoop, Anouk Willemsen, Ines Sifaoui, Iñigo Arberas-Jiménez, Frederik Schulz, Jacob Lorenzo-Morales, Matthias Horn   +12 more
doaj   +1 more source

Temporal and Spatial Survey on the Abundance of Amoebae and Bacteria in an Estuary and the Role of Environmental Parameters

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
Free‐living amoebae and bacteria were monitored along a salinity gradient over 1 year. Naegleria and Vibrio were the most represented genera, with salinity and dissolved oxygen identified as key factors structuring amoebae diversity and associated bacterial communities under changing environmental conditions.
Gaëlle Bednarek, Hélène Agogué, Arno Bringer, Tony Agion, Vincent Delafont, Yann Héchard   +5 more
wiley   +1 more source

A Deeply Branching Lineage in Heterolobosea (Discoba) With Multiflagellated and Multigrooved Life Stages

Journal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT Several distantly related, deep‐branching lineages within the eukaryotic tree of life share what is known as the “typical excavate” morphology. This cell architecture includes a suspension‐feeding ventral groove, supported by complex and specific structures of the cytoskeleton, and a vane‐bearing posterior flagellum.
Kristina I. Prokina, Naoji Yubuki, Luis Javier Galindo, Guifré Torruella, Yuji Inagaki, Koji Iwamoto, Purificación López‐García, David Moreira   +7 more
wiley   +1 more source

Flavonoids as Promising Akt1 Inhibitors in Cancer Medicine: Insights From Molecular Docking, Dynamics, DFT Calculations, and In Vitro Validation

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background The PI3K/Akt/mTOR signaling pathway is commonly deregulated in different types of cancers, contributing to tumor proliferation, persistence, and resistance to treatment. Akt1, a crucial kinase within this pathway, plays a critical role in tumor progression and the occurrence of therapeutic resistance.
Shokoofeh Jamshidi, Ali Eghbalian, Setareh Shojaei, Amir Taherkhani, Mehran Feizi‐Dehnayebi   +4 more
wiley   +1 more source

Population Structure in Naegleria fowleri as Revealed by Microsatellite Markers. [PDF]

PLoS ONE, 2016
Naegleria sp. is a free living amoeba belonging to the Heterolobosea class. Over 40 species of Naegleria were identified and recovered worldwide in different habitats such as swimming pools, freshwater lakes, soil or dust. Among them, N.
Bénédicte Coupat-Goutaland, Estelle Régoudis, Matthieu Besseyrias, Angélique Mularoni, Marie Binet, Pascaline Herbelin, Michel Pélandakis   +6 more
doaj   +1 more source

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes

Molecular Microbiology, Volume 124, Issue 1, Page 54-65, July 2025.
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet, Raphael Munoz‐Ruiz, Imen Ayadi, Alixia Bourbon, Erwann Pain, Joseph Oddy, Pierre Cosson   +6 more
wiley   +1 more source

Experimental meningoencephalitis by Naegleria fowleri in mice

The Korean Journal of Parasitology, 1984
Experimentally, primary amoebic meningoencephalitis (PAM) is induced by Naegleria fowleri in mouse and development of PAM may be influenced by the strain, weight and sex of mouse, and inoculum size of N. fowleri trophozoite. In this paper, the effect of these factors on PAM development of mouse was studied. N.
Myoung Hee, Ahn, Kyung Il, Im
openaire   +2 more sources

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, Volume 3, Issue 2, Page 148-157, June 2025.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Naegleria fowleri in Pakistan [PDF]

The Lancet Infectious Diseases, 2020
Mahwish, Ali, Syed Babar, Jamal, Syeda Mehpara, Farhat   +2 more
openaire   +2 more sources