Results 251 to 260 of about 176,389 (357)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Dietary Inflammatory Index and risk of nonalcoholic fatty liver disease: nonlinear associations, metabolic mediation, and external validation. [PDF]

Front Nutr
Chen T, Zheng G, Tan H, Guo L, Liu Y, Qian X, Feng S, Zhang Y.   +7 more
europepmc   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

The FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

Prevalence of metabolic dysfunction associated steatotic liver disease in type 2 diabetes mellitus in India: A systematic review and meta-analysis. [PDF]

Indian J Med Res
Singhai A, Meena R, Joshi R, Khadanga S, Jhaj R, Goyal A, Wakode S.   +6 more
europepmc   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Gut microbiota and the gut-liver axis in MASLD: mechanisms, immune regulation and therapeutic opportunities. [PDF]

Front Pharmacol
Liu J, Zhao M, Wang S, Zhang C, Zhong Y, Qu Y.   +5 more
europepmc   +1 more source

Association Between Locomotive Syndrome and Metabolic Dysfunction‐Associated Steatotic Liver Disease in a Health Examination Cohort: A Cross‐Sectional Study

Hepatology Research, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is associated with liver fat and other health problems. In this study of 7776 adults who underwent health examinations, early mobility impairment was more common in individuals with MASLD.
Shinya Yokoyama, Takanori Ito, Taku Tanaka, Hiroaki Hiraiwa, Takashi Honda, Yoji Ishizu, Norihiro Imai, Kenta Yamamoto, Kazuki Sahara, Tetsuhito Kojima, Naoyoshi Kariya, Hiroki Kawashima   +11 more
wiley   +1 more source

Sex-specific co-occurrence patterns of Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease among patients with colorectal cancer: a retrospective EMR-based series. [PDF]

Front Med (Lausanne)
Akbarian Khorasgani M, Katouzi P, Khalifeh Hadi M, Amarloei M, Kianpourhafshejani Y, Sultana S, Al-Mlawi MHMA, Zeng Y, Lu J.   +8 more
europepmc   +1 more source

UltRaSoUnd‐guided evaLuAtion of metabolic health in a cohort of midlife women with HIV: The URSULA study

HIV Medicine, EarlyView.
Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno, Davide Capruzzi, Antonio Cianciaruso, Nicola Colavito, Felicia Dalitto, Vincenzo Giliberti, Vittoria Lobalsamo, Giuliana Metrangolo, Marica Noviello, Alessandra Vigna, Maurizio Zarcone, Francesco Di Gennaro, Vincenzo Ostilio Palmieri, Annalisa Saracino   +13 more
wiley   +1 more source

Association of Domain-Specific Physical Activities with Non-Alcoholic Fatty Liver Disease in Workers: A Focus on Gender Differences. [PDF]

Metabolites
Baek SU, Yoon JH.
europepmc   +1 more source