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The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment [PDF]

open access: yesLiver International, 2016
BACKGROUND & AIMS Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. An increasing number of reports describe HCC in the setting of obesity and diabetes, two major risk factors for non-alcoholic fatty liver disease ...
Margini, Cristina   +1 more
exaly   +2 more sources
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Microbiota, Obesity and NAFLD

2018
Non-alcoholic fatty liver disease (NAFLD) is an increasingly important cause of chronic liver disease globally. Similar to metabolic syndrome and obesity, NAFLD is associated with alternations in the gut microbiota and its related biological pathways. While the exact pathophysiology of NAFLD remains largely unknown, changes in intestinal inflammation ...
Louis H S, Lau, Sunny H, Wong
openaire   +2 more sources

Noninvasive evaluation of NAFLD

Nature Reviews Gastroenterology & Hepatology, 2013
A common clinical concern in patients with NAFLD is whether they have NASH or simple steatosis and, more importantly, what the stage of fibrosis is and whether the level of fibrosis has increased over time. Such concern is based on the fact that patients with NAFLD with advanced fibrosis are at greatest risk of developing complications of end-stage ...
Laurent, Castera   +2 more
openaire   +2 more sources

NAFLD/NASH

Journal of Hepatology, 2022
Elisabetta Bugianesi, Salvatore Petta
openaire   +2 more sources

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease (NAFLD): Expert Review.

Gastroenterology, 2020
Nonalcoholic fatty liver disease. (NAFLD) is a leading etiology for chronic liver disease with global public health impact, affecting over 25% of the global population.
Z. Younossi, K. Corey, Joseph K. Lim
semanticscholar   +1 more source

Unexpected Rapid Increase in the Burden of NAFLD in China From 2008 to 2018: A Systematic Review and Meta‐Analysis

Hepatology, 2019
With rapid lifestyle transitions, the increasing burden of nonalcoholic fatty liver disease (NAFLD) in China has emerged as a major public health issue.
Feng Zhou   +9 more
semanticscholar   +1 more source

NAFLD and diabetes mellitus

Nature Reviews Gastroenterology & Hepatology, 2016
The liver constitutes a key organ in systemic metabolism, contributing substantially to the development of insulin resistance and type 2 diabetes mellitus (T2DM). The mechanisms underlying these processes are not entirely understood, but involve hepatic fat accumulation, alterations of energy metabolism and inflammatory signals derived from various ...
Herbert, Tilg   +2 more
openaire   +2 more sources

NAFLD and Statins

Digestive Diseases and Sciences, 2020
Vasilios G. Athyros   +2 more
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Editorial: NAFLD, NAFLD, or MASLD: what's in a name?

Alimentary Pharmacology & Therapeutics
LINKED CONTENTThis article is linked to Kim et al paper.
Maryam Zafer, Shravan Dave
openaire   +2 more sources

The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments

Nature reviews: Gastroenterology & hepatology, 2021
G. Targher, K. Corey, C. Byrne, M. Roden
semanticscholar   +1 more source

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