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The story of HCC in NAFLD: from epidemiology, across pathogenesis, to prevention and treatment [PDF]
BACKGROUND & AIMS Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. An increasing number of reports describe HCC in the setting of obesity and diabetes, two major risk factors for non-alcoholic fatty liver disease ...
Margini, Cristina +1 more
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2018
Non-alcoholic fatty liver disease (NAFLD) is an increasingly important cause of chronic liver disease globally. Similar to metabolic syndrome and obesity, NAFLD is associated with alternations in the gut microbiota and its related biological pathways. While the exact pathophysiology of NAFLD remains largely unknown, changes in intestinal inflammation ...
Louis H S, Lau, Sunny H, Wong
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Non-alcoholic fatty liver disease (NAFLD) is an increasingly important cause of chronic liver disease globally. Similar to metabolic syndrome and obesity, NAFLD is associated with alternations in the gut microbiota and its related biological pathways. While the exact pathophysiology of NAFLD remains largely unknown, changes in intestinal inflammation ...
Louis H S, Lau, Sunny H, Wong
openaire +2 more sources
Noninvasive evaluation of NAFLD
Nature Reviews Gastroenterology & Hepatology, 2013A common clinical concern in patients with NAFLD is whether they have NASH or simple steatosis and, more importantly, what the stage of fibrosis is and whether the level of fibrosis has increased over time. Such concern is based on the fact that patients with NAFLD with advanced fibrosis are at greatest risk of developing complications of end-stage ...
Laurent, Castera +2 more
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Gastroenterology, 2020
Nonalcoholic fatty liver disease. (NAFLD) is a leading etiology for chronic liver disease with global public health impact, affecting over 25% of the global population.
Z. Younossi, K. Corey, Joseph K. Lim
semanticscholar +1 more source
Nonalcoholic fatty liver disease. (NAFLD) is a leading etiology for chronic liver disease with global public health impact, affecting over 25% of the global population.
Z. Younossi, K. Corey, Joseph K. Lim
semanticscholar +1 more source
Hepatology, 2019
With rapid lifestyle transitions, the increasing burden of nonalcoholic fatty liver disease (NAFLD) in China has emerged as a major public health issue.
Feng Zhou +9 more
semanticscholar +1 more source
With rapid lifestyle transitions, the increasing burden of nonalcoholic fatty liver disease (NAFLD) in China has emerged as a major public health issue.
Feng Zhou +9 more
semanticscholar +1 more source
Nature Reviews Gastroenterology & Hepatology, 2016
The liver constitutes a key organ in systemic metabolism, contributing substantially to the development of insulin resistance and type 2 diabetes mellitus (T2DM). The mechanisms underlying these processes are not entirely understood, but involve hepatic fat accumulation, alterations of energy metabolism and inflammatory signals derived from various ...
Herbert, Tilg +2 more
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The liver constitutes a key organ in systemic metabolism, contributing substantially to the development of insulin resistance and type 2 diabetes mellitus (T2DM). The mechanisms underlying these processes are not entirely understood, but involve hepatic fat accumulation, alterations of energy metabolism and inflammatory signals derived from various ...
Herbert, Tilg +2 more
openaire +2 more sources
Editorial: NAFLD, NAFLD, or MASLD: what's in a name?
Alimentary Pharmacology & TherapeuticsLINKED CONTENTThis article is linked to Kim et al paper.
Maryam Zafer, Shravan Dave
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The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments
Nature reviews: Gastroenterology & hepatology, 2021G. Targher, K. Corey, C. Byrne, M. Roden
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