Results 31 to 40 of about 6,183 (297)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Concept of Nafs in the Alquran

open access: yesSuluah Pasaman, 2023
Psychology is a science that studies human experiences, such as feelings, five senses, thoughts, and will. Islamic psychology studies convey problems regarding human psychology, inner intricacies, and ruhual solutions that refer to Islamic normative law.
Lelti Saputri Yani   +3 more
openaire   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Nefis Nazariyesi Çerçevesinde Fahreddin er-Râzî’nin Ahlâk Düşüncesi

open access: yesCumhuriyet Üniversitesi İlahiyat Fakültesi Dergisi, 2014
Kelâm, felsefe, tefsir ve usûl-i fıkıh alanlarındaki çalışmalarıyla tanınan Eş’arî âlimi Fahreddin er-Râzî, eserlerinde genellikle akıl ve vahiy arasındaki uyum ve irtibata işaret etmektedir.
Asiye Aykıt
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The Term “Nafs” in The Qur’ān

open access: yesKader, 2023
The definition, nature, characteristics, and identification of the nafs are among the most fundamental problems in both metaphysics and theology. The manner in which the subject of the nafs is addressed even provides the opportunity to scrutinize the ...
Tuğba Günal
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Konsep Nafs Dalam Sudut Pandang Ibnu Sina

open access: yes, 2022
Pembahasan mengenai jiwa sangat penting untuk dibicarakan, hal ini berdasarkan pengalaman perdaban Barat yang tidak bisa untuk membuktikan keberadaan nafs atau jiwa.
Alif Reynika Rahman
core   +1 more source

PEMIKIRAN PARA FILOSOF MUSLIM TENTANG JIWA

open access: yesAn-Nida', 2014
Tulisan ini memaparkan pemikiran beberapa filosof muslim tentang jiwa. Banyak pemikiran dalam memahami keesaan Allah yang diangkat oleh berbagai aliran dalam Islam, tetapi setelah dicermati maka semuanya mengerucut pada dua kelompok saja, yaitu pemikiran
Afrizal M
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler   +20 more
wiley   +1 more source

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